FTSQ_MYCTO
ID FTSQ_MYCTO Reviewed; 314 AA.
AC P9WNA0; L0TBG9; O06226; P64168;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=Cell division protein FtsQ {ECO:0000255|HAMAP-Rule:MF_00911};
GN Name=ftsQ {ECO:0000255|HAMAP-Rule:MF_00911}; OrderedLocusNames=MT2210;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- FUNCTION: Essential cell division protein. {ECO:0000255|HAMAP-
CC Rule:MF_00911}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00911};
CC Single-pass type II membrane protein {ECO:0000255|HAMAP-Rule:MF_00911}.
CC Note=Localizes to the division septum. {ECO:0000255|HAMAP-
CC Rule:MF_00911}.
CC -!- SIMILARITY: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_00911}.
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DR EMBL; AE000516; AAK46494.1; -; Genomic_DNA.
DR PIR; C70579; C70579.
DR RefSeq; WP_003411157.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WNA0; -.
DR SMR; P9WNA0; -.
DR EnsemblBacteria; AAK46494; AAK46494; MT2210.
DR KEGG; mtc:MT2210; -.
DR PATRIC; fig|83331.31.peg.2383; -.
DR HOGENOM; CLU_047677_1_2_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0032153; C:cell division site; IEA:UniProtKB-UniRule.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0090529; P:cell septum assembly; IEA:InterPro.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00911; FtsQ_subfam; 1.
DR InterPro; IPR005548; Cell_div_FtsQ/DivIB_C.
DR InterPro; IPR026579; FtsQ.
DR InterPro; IPR034746; POTRA.
DR InterPro; IPR013685; POTRA_FtsQ_type.
DR Pfam; PF03799; FtsQ; 1.
DR Pfam; PF08478; POTRA_1; 1.
DR PROSITE; PS51779; POTRA; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..314
FT /note="Cell division protein FtsQ"
FT /id="PRO_0000427163"
FT TOPO_DOM 1..99
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00911"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00911"
FT TOPO_DOM 121..314
FT /note="Extracellular"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00911"
FT DOMAIN 124..192
FT /note="POTRA"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01115"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 314 AA; 33934 MW; FD8C00B41A329D60 CRC64;
MTEHNEDPQI ERVADDAADE EAVTEPLATE SKDEPAEHPE FEGPRRRARR ERAERRAAQA
RATAIEQARR AAKRRARGQI VSEQNPAKPA ARGVVRGLKA LLATVVLAVV GIGLGLALYF
TPAMSAREIV IIGIGAVSRE EVLDAARVRP ATPLLQIDTQ QVADRVATIR RVASARVQRQ
YPSALRITIV ERVPVVVKDF SDGPHLFDRD GVDFATDPPP PALPYFDVDN PGPSDPTTKA
ALQVLTALHP EVASQVGRIA APSVASITLT LADGRVVIWG TTDRCEEKAE KLAALLTQPG
RTYDVSSPDL PTVK
