ID   FTSW_MESVI              Reviewed;         415 AA.
AC   Q9MUM4;
DT   27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Putative peptidoglycan glycosyltransferase FtsW {ECO:0000250|UniProtKB:O07639};
DE            Short=PGT {ECO:0000250|UniProtKB:O07639};
DE            EC=2.4.1.129 {ECO:0000250|UniProtKB:O07639};
DE   AltName: Full=Peptidoglycan polymerase {ECO:0000250|UniProtKB:O07639};
DE            Short=PG polymerase {ECO:0000250|UniProtKB:O07639};
GN   Name=ftsW;
OS   Mesostigma viride (Green alga).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Mesostigmatophyceae;
OC   Mesostigmatales; Mesostigmataceae; Mesostigma.
OX   NCBI_TaxID=41882;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-296 / KY-14 / CCMP 2046;
RX   PubMed=10688199; DOI=10.1038/35001059;
RA   Lemieux C., Otis C., Turmel M.;
RT   "Ancestral chloroplast genome in Mesostigma viride reveals an early branch
RT   of green plant evolution.";
RL   Nature 403:649-652(2000).
CC   -!- FUNCTION: Could play a role in chloroplast division/peptidoglycan
CC       biosynthesis.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-
CC         Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-
CC         (1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-
CC         cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-
CC         D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl
CC         diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+);
CC         Xref=Rhea:RHEA:23708, Rhea:RHEA-COMP:9602, Rhea:RHEA-COMP:9603,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:58405, ChEBI:CHEBI:60033,
CC         ChEBI:CHEBI:78435; EC=2.4.1.129;
CC         Evidence={ECO:0000250|UniProtKB:P39604};
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the SEDS family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF166114; AAF43874.1; -; Genomic_DNA.
DR   RefSeq; NP_038436.1; NC_002186.1.
DR   AlphaFoldDB; Q9MUM4; -.
DR   SMR; Q9MUM4; -.
DR   GeneID; 800983; -.
DR   GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008955; F:peptidoglycan glycosyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051301; P:cell division; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   InterPro; IPR018365; Cell_cycle_FtsW-rel_CS.
DR   InterPro; IPR001182; FtsW/RodA.
DR   PANTHER; PTHR30474; PTHR30474; 1.
DR   Pfam; PF01098; FTSW_RODA_SPOVE; 1.
DR   PROSITE; PS00428; FTSW_RODA_SPOVE; 1.
PE   3: Inferred from homology;
KW   Cell shape; Chloroplast; Glycosyltransferase; Membrane;
KW   Peptidoglycan synthesis; Plastid; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..415
FT                   /note="Putative peptidoglycan glycosyltransferase FtsW"
FT                   /id="PRO_0000062714"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        306..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        367..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   415 AA;  46814 MW;  E35116E9692EC782 CRC64;
     MIRRFVSICI QLIEDLLIGG WNSIWYYLFP IMHPRCANWW SVARWLQWLT FLWLSIGLIV
     LCSASYPSAQ FEFNDGLYYV KRQLLWTILG ILEFNLLTRL LIKDILKISS LGIIFSFLCL
     LLTFPMGISV NGASRWIAIG PILLQPSEII KPFLILQSSY IFSQWDNISY SKKIFWVILF
     ISIIGSILIQ PNLSTASLCG AIIWLVALTA GIHWFYLNSI LSIGAVTALI SLGSQEYQRQ
     RIISFLNPWA NPTSIGYQLV QSLLAVGSGR LTGSGISCSY QKLFYLPIQY TDFIFSVFSE
     EFGLLGAFLF ISLLIIYFSL GMIVVLSNKS KVNRLLALGC IMVLVGQSLI NIGVSVGILP
     TTGLPLPFFS YGGNSILATF FVSAILIRVA IETEIDNRIN IFSLLNKQSI FYWFK