ID   FTSX_HAEIN              Reviewed;         310 AA.
AC   P44872;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Cell division protein FtsX;
GN   Name=ftsX; OrderedLocusNames=HI_0770;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Part of the ABC transporter FtsEX involved in cellular
CC       division. {ECO:0000250}.
CC   -!- SUBUNIT: Forms a membrane-associated complex with FtsE. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC-4 integral membrane protein family. FtsX
CC       subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L42023; AAC22428.1; -; Genomic_DNA.
DR   PIR; I64091; I64091.
DR   RefSeq; NP_438929.1; NC_000907.1.
DR   RefSeq; WP_005660149.1; NC_000907.1.
DR   AlphaFoldDB; P44872; -.
DR   SMR; P44872; -.
DR   STRING; 71421.HI_0770; -.
DR   EnsemblBacteria; AAC22428; AAC22428; HI_0770.
DR   KEGG; hin:HI_0770; -.
DR   PATRIC; fig|71421.8.peg.809; -.
DR   eggNOG; COG2177; Bacteria.
DR   HOGENOM; CLU_073546_0_0_6; -.
DR   OMA; ETGIMRL; -.
DR   PhylomeDB; P44872; -.
DR   BioCyc; HINF71421:G1GJ1-810-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR   GO; GO:0009276; C:Gram-negative-bacterium-type cell wall; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; ISS:UniProtKB.
DR   InterPro; IPR004513; ABC_transpt_FtsX.
DR   InterPro; IPR040690; FtsX_ECD.
DR   PANTHER; PTHR47755; PTHR47755; 1.
DR   Pfam; PF18075; FtsX_ECD; 1.
DR   PIRSF; PIRSF003097; FtsX; 1.
DR   TIGRFAMs; TIGR00439; ftsX; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..310
FT                   /note="Cell division protein FtsX"
FT                   /id="PRO_0000166794"
FT   TOPO_DOM        1..31
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        53..176
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        198..234
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        256..279
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        280..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        301..310
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   310 AA;  35033 MW;  4F1EB7D259257E38 CRC64;
     MSRSTDASVF VQTAYTLRAV WADLWQRKFG TLLTILVIAV SLTIPTVSYL MWKNLHLATT
     QFYPESELTI YLHKNLSEEN ANLVVEKIRQ QKGVESLNYV SRQESLKEFK SWSGFGEELE
     ILDDNPLPAV VIVKPTSEFN VSEKRDELRT NLNKIKGVQE VRLDNDWMEK LTALSWLIAH
     VAIFCTVLMT IAVFLVIGNS IRSDVYSSRS SIDVMKLLGA TDQFILRPYL YTGMIYALLG
     GLVAAIFSSF IISYFTSAVK YVTDIFAVQF SLNGLGVGEF VFLLVCCLIM GYVGAWIAAT
     RHIAMMERKE