ID   FUCK_SALTY              Reviewed;         472 AA.
AC   Q8ZMC5;
DT   11-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=L-fuculokinase {ECO:0000255|HAMAP-Rule:MF_00986};
DE            EC=2.7.1.51 {ECO:0000255|HAMAP-Rule:MF_00986};
DE   AltName: Full=L-fuculose kinase {ECO:0000255|HAMAP-Rule:MF_00986};
GN   Name=fucK {ECO:0000255|HAMAP-Rule:MF_00986}; OrderedLocusNames=STM2977;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Catalyzes the phosphorylation of L-fuculose.
CC       {ECO:0000255|HAMAP-Rule:MF_00986}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-fuculose = ADP + H(+) + L-fuculose 1-phosphate;
CC         Xref=Rhea:RHEA:12376, ChEBI:CHEBI:15378, ChEBI:CHEBI:17617,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:57846, ChEBI:CHEBI:456216;
CC         EC=2.7.1.51; Evidence={ECO:0000255|HAMAP-Rule:MF_00986};
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00986};
CC   -!- PATHWAY: Carbohydrate degradation; L-fucose degradation; L-lactaldehyde
CC       and glycerone phosphate from L-fucose: step 2/3. {ECO:0000255|HAMAP-
CC       Rule:MF_00986}.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family. {ECO:0000255|HAMAP-
CC       Rule:MF_00986}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE006468; AAL21855.1; -; Genomic_DNA.
DR   RefSeq; NP_461896.1; NC_003197.2.
DR   RefSeq; WP_000806780.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZMC5; -.
DR   SMR; Q8ZMC5; -.
DR   STRING; 99287.STM2977; -.
DR   PaxDb; Q8ZMC5; -.
DR   EnsemblBacteria; AAL21855; AAL21855; STM2977.
DR   GeneID; 1254500; -.
DR   KEGG; stm:STM2977; -.
DR   PATRIC; fig|99287.12.peg.3153; -.
DR   HOGENOM; CLU_009281_11_2_6; -.
DR   OMA; SDLWMQI; -.
DR   PhylomeDB; Q8ZMC5; -.
DR   BioCyc; SENT99287:STM2977-MON; -.
DR   UniPathway; UPA00563; UER00625.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008737; F:L-fuculokinase activity; IBA:GO_Central.
DR   GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IBA:GO_Central.
DR   GO; GO:0042355; P:L-fucose catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0019301; P:rhamnose catabolic process; IBA:GO_Central.
DR   HAMAP; MF_00986; Fuculokinase; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; Carb_kinase_FGGY_C.
DR   InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   InterPro; IPR013450; Fuculokinase.
DR   PANTHER; PTHR10196:SF60; PTHR10196:SF60; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   PIRSF; PIRSF000538; GlpK; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   TIGRFAMs; TIGR02628; fuculo_kin_coli; 1.
DR   PROSITE; PS00933; FGGY_KINASES_1; 1.
DR   PROSITE; PS00445; FGGY_KINASES_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Carbohydrate metabolism; Fucose metabolism; Kinase;
KW   Nucleotide-binding; Reference proteome; Transferase.
FT   CHAIN           1..472
FT                   /note="L-fuculokinase"
FT                   /id="PRO_0000059427"
SQ   SEQUENCE   472 AA;  51674 MW;  0AAC72FC94BCBF72 CRC64;
     MKQDVILVLD CGATNVRAIA VDRQGKIVAR ASTANASDIA AENSAWHQWS LDAILQRFAD
     CCRSLSSALS ECVVRGITVT TFGVDGALVD AQGKLLYPVI SWKCPRTAAV METIERFISP
     RQLQTLSGVG AFSFNTLYKL VWLKENHPRL LEQAHCWLFI SSLINHRLTG EFTTDITMAG
     TSQLLDIHQR DFSPEILQAT GLARRLFPRI VEAGAPIGTL QTDAARLLGL PAGVPVISAG
     HDTQFALFGA GAQQGEPVLS SGTWEILMVR SGQVDTSLLS QYPGSTCELD SQSGLYNPGM
     QWLASGVLEW VRKLLWTPET PWQTLIDEAR AIPAGAEGVR MQCDLLACQN AGWQGVTLNT
     TRGHFYRAAL EGLTAQLQRN LRTLEKIGHF NATELLLVGG GSRNALWNQI KANQLDIPIK
     VLDDAETTVA GAAMFGWYGV GEFSSPEQAR AQVNYQYRYF WPQTEPEIIE GV