ID   FUCT1_MONBE             Reviewed;         333 AA.
AC   A9UUB8;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=GDP-fucose transporter 1;
DE   AltName: Full=Solute carrier family 35 member C1 homolog;
GN   Name=slc35c1; Synonyms=fuct1; ORFNames=18313;
OS   Monosiga brevicollis (Choanoflagellate).
OC   Eukaryota; Choanoflagellata; Craspedida; Salpingoecidae; Monosiga.
OX   NCBI_TaxID=81824;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MX1 / ATCC 50154;
RX   PubMed=18273011; DOI=10.1038/nature06617;
RG   JGI Sequencing;
RA   King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J.,
RA   Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D.,
RA   Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M.,
RA   Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S.,
RA   Richter D.J., Salamov A., Bork P., Lim W.A., Manning G., Miller W.T.,
RA   McGinnis W., Shapiro H., Tjian R., Grigoriev I.V., Rokhsar D.;
RT   "The genome of the choanoflagellate Monosiga brevicollis and the origin of
RT   metazoans.";
RL   Nature 451:783-788(2008).
CC   -!- FUNCTION: Involved in GDP-fucose import from the cytoplasm into the
CC       Golgi lumen. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Multi-
CC       pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TPT transporter family. SLC35C subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CH991546; EDQ91067.1; -; Genomic_DNA.
DR   RefSeq; XP_001744364.1; XM_001744312.1.
DR   AlphaFoldDB; A9UUB8; -.
DR   SMR; A9UUB8; -.
DR   STRING; 81824.XP_001744364.1; -.
DR   EnsemblProtists; EDQ91067; EDQ91067; MONBRDRAFT_18313.
DR   GeneID; 5889609; -.
DR   KEGG; mbr:MONBRDRAFT_18313; -.
DR   eggNOG; KOG1442; Eukaryota.
DR   InParanoid; A9UUB8; -.
DR   OMA; GLQIKYT; -.
DR   Proteomes; UP000001357; Unassembled WGS sequence.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IBA:GO_Central.
DR   GO; GO:0005457; F:GDP-fucose transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0036085; P:GDP-fucose import into Golgi lumen; IBA:GO_Central.
DR   GO; GO:0036066; P:protein O-linked fucosylation; IBA:GO_Central.
DR   InterPro; IPR029666; GDP-fucose_transp.
DR   InterPro; IPR004853; Sugar_P_trans_dom.
DR   PANTHER; PTHR11132:SF255; PTHR11132:SF255; 1.
DR   Pfam; PF03151; TPT; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Reference proteome; Sugar transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..333
FT                   /note="GDP-fucose transporter 1"
FT                   /id="PRO_0000343211"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        239..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   333 AA;  36727 MW;  BD9A3D575E327F8F CRC64;
     MSPGQDATLL ERSIKIAFVV ALYWVVSISM VFLNKYLLSE VSLDAPMFVT WFQCVVAVVT
     CFILGELRSY HPALEMFPRF AFDTHVAMKV LPLSLVFVGM IAFNNLALKF VGVAFYNVGR
     SLTTIFNVLL SFFMLQQRTS MPALLMCGVI VAGFFVGVNK EQEQADLTMA GIMYGVLASL
     CVALNAIYIK KVMPFVDNDM WKLTAYNNMN AIFLFLPVIT FMGEIPDIAA SEDVYSGNYW
     FLMTVAGLLG IAIGLVSMLQ INVTSPLTHN ISGTSKACAQ TILALQLNDE SRTATWWLGN
     VFVLGGSLGY VLVKRAEMKR DLEKVPSSAD SKA