ID   FUJ5_GIBF5              Reviewed;         413 AA.
AC   S0EBQ6;
DT   25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2013, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Fujikurins biosynthesis cluster transcription factor FFUJ_12243 {ECO:0000303|PubMed:26192387};
GN   ORFNames=FFUJ_12243;
OS   Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae
OS   and foot rot disease fungus) (Fusarium fujikuroi).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium fujikuroi species complex.
OX   NCBI_TaxID=1279085;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], IDENTIFICATION, FUNCTION,
RP   AND INDUCTION.
RC   STRAIN=CBS 195.34 / IMI 58289 / NRRL A-6831;
RX   PubMed=23825955; DOI=10.1371/journal.ppat.1003475;
RA   Wiemann P., Sieber C.M.K., von Bargen K.W., Studt L., Niehaus E.-M.,
RA   Espino J.J., Huss K., Michielse C.B., Albermann S., Wagner D.,
RA   Bergner S.V., Connolly L.R., Fischer A., Reuter G., Kleigrewe K., Bald T.,
RA   Wingfield B.D., Ophir R., Freeman S., Hippler M., Smith K.M., Brown D.W.,
RA   Proctor R.H., Muensterkoetter M., Freitag M., Humpf H.-U., Gueldener U.,
RA   Tudzynski B.;
RT   "Deciphering the cryptic genome: genome-wide analyses of the rice pathogen
RT   Fusarium fujikuroi reveal complex regulation of secondary metabolism and
RT   novel metabolites.";
RL   PLoS Pathog. 9:E1003475-E1003475(2013).
RN   [2]
RP   FUNCTION.
RX   PubMed=26192387; DOI=10.1021/np5008137;
RA   von Bargen K.W., Niehaus E.M., Krug I., Bergander K., Wuerthwein E.U.,
RA   Tudzynski B., Humpf H.U.;
RT   "Isolation and structure elucidation of fujikurins A-D: products of the
RT   PKS19 gene cluster in Fusarium fujikuroi.";
RL   J. Nat. Prod. 78:1809-1815(2015).
CC   -!- FUNCTION: Transcription factor that regulates the expression of the
CC       gene cluster that mediates the biosynthesis of fujikurins
CC       (PubMed:23825955, PubMed:26192387). {ECO:0000305|PubMed:23825955,
CC       ECO:0000305|PubMed:26192387}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- INDUCTION: The fujikurins gene cluster is specifically expressed during
CC       rice infection (PubMed:23825955). {ECO:0000269|PubMed:23825955}.
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DR   EMBL; HF679030; CCT72381.1; -; Genomic_DNA.
DR   AlphaFoldDB; S0EBQ6; -.
DR   EnsemblFungi; CCT72381; CCT72381; FFUJ_12243.
DR   VEuPathDB; FungiDB:FFUJ_12243; -.
DR   HOGENOM; CLU_062050_0_0_1; -.
DR   Proteomes; UP000016800; Chromosome 8.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..413
FT                   /note="Fujikurins biosynthesis cluster transcription factor
FT                   FFUJ_12243"
FT                   /id="PRO_0000442011"
FT   DNA_BIND        7..47
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          145..173
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   413 AA;  45324 MW;  D2F4F43517BA7538 CRC64;
     MSHRQSCDRC RQQKVRCLRD ESQGGAGNKA RASFSRCERC TKASVDCVYS LKSRSNRPNA
     HQPIHNQVDA DPQTLVGPSW FGQGLFCQAA SGSLGPDYDD LAGQFADLDG AEFNGWDGNL
     DVIPSLSMSS LNTLAAPAAM VSQDISPTKD HHDNNHMQEP EADDDDESNN GHDQDAIQEL
     SLQLTAISQR ATRAKRRLHR AGCPPPTVSS PEVNEAFEDT NNLLRIANNI TNACAHLCDE
     ASSNSITLDY GLVFSALASH QHLLALFKAI CHLIQRYLES MTSANQHRQQ QQQRLHDGDI
     GPSSVAQFVM VLQLLTYLIN RMDRNLAQVN GPHGHGLETS LGGQATPITP STGYQDIVQS
     MLIHRGDKNN TTGSSQSLPI IGQVVLGAIP DEHKRLRQVI QELQTRIERS EIQ