ID   FUT10_CHICK             Reviewed;         475 AA.
AC   Q8AWB5;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 2.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Alpha-(1,3)-fucosyltransferase 10;
DE            EC=2.4.1.-;
DE   AltName: Full=Fucosyltransferase X;
DE            Short=Fuc-TX;
DE            Short=FucT-X;
DE   AltName: Full=Galactoside 3-L-fucosyltransferase 10;
DE            Short=Fucosyltransferase 10;
GN   Name=FUT10;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Candelier J.-J., Martinez-Duncker I., Oriol R., Mollicone R.;
RT   "Cloning expression and genomic organization of a new human alpha3-
RT   fucosyltransferase (FUT10).";
RL   Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable fucosyltransferase. {ECO:0000250}.
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane
CC       {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 10 family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAD59689.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AJ535692; CAD59689.1; ALT_FRAME; mRNA.
DR   AlphaFoldDB; Q8AWB5; -.
DR   SMR; Q8AWB5; -.
DR   STRING; 9031.ENSGALP00000036990; -.
DR   CAZy; GT10; Glycosyltransferase Family 10.
DR   PaxDb; Q8AWB5; -.
DR   VEuPathDB; HostDB:geneid_395073; -.
DR   eggNOG; KOG2619; Eukaryota.
DR   InParanoid; Q8AWB5; -.
DR   PhylomeDB; Q8AWB5; -.
DR   UniPathway; UPA00378; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.11660; -; 1.
DR   InterPro; IPR017176; Alpha-1_3-FUT_met.
DR   InterPro; IPR031481; Glyco_tran_10_N.
DR   InterPro; IPR001503; Glyco_trans_10.
DR   InterPro; IPR038577; GT10-like_C_sf.
DR   PANTHER; PTHR11929; PTHR11929; 1.
DR   Pfam; PF17039; Glyco_tran_10_N; 1.
DR   Pfam; PF00852; Glyco_transf_10; 1.
DR   PIRSF; PIRSF037332; Alpha1_3FUT_met; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Glycosyltransferase; Golgi apparatus; Membrane;
KW   Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..475
FT                   /note="Alpha-(1,3)-fucosyltransferase 10"
FT                   /id="PRO_0000299005"
FT   TOPO_DOM        1..8
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        9..29
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        30..475
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        107
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        165
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        315
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        462
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   475 AA;  55832 MW;  31733F01F12E6B65 CRC64;
     MVRMRRKRLW ASCICFAAFF FLLVTLQVIT ELGNSENKAP AVSSLHSGPL KPDERHASQL
     KKNELYSNFR TEPDTDHYPI LLWWSPLTGE TGRSGQCGED VCFFTINKTY QHSQMTRAFL
     FYGTDFSIDS LPLPRKDHHD WALFHEESPK NNYKLFHEPA ITLFNHTATF SRHSHLPLTT
     QYLESIEVLR SLRHMIPVQM KNSLRKRLAP LVYVQSDCNA PSDRDSYVRE LMCHIEVDSY
     GECLHNRDLP QHLRNPSAMD DGNFYKILAQ YKFILAFENA ICEDYITEKL WRPLMLGVVP
     VYFGSPSIID WLPSNKSAIL VSSFSHPREL ARYIKTLDQN DQEYEAYLEW KLKGDISNPR
     LLTAMKERKW GVQDVTQDNY IDTFECMVCN RVWENIRREE KGWLPQRWSA QVNHLNCPKP
     EAFWFSSSNP SQSSLQEMWI ASFEQSKKEA WALRQLVERN RNFTTQEFWM LVFKQ