FUT11_CHICK
ID FUT11_CHICK Reviewed; 505 AA.
AC Q8AWC7;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Alpha-(1,3)-fucosyltransferase 11;
DE EC=2.4.1.-;
DE AltName: Full=Fucosyltransferase XI;
DE Short=Fuc-TXI;
DE Short=FucT-XI;
DE AltName: Full=Galactoside 3-L-fucosyltransferase 11;
DE Short=Fucosyltransferase 11;
GN Name=FUT11;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Candelier J.-J., Martinez-Duncker I., Oriol R., Mollicone R.;
RT "Cloning expression and genomic organization of a new human alpha3-
RT fucosyltransferase (FUT11).";
RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable fucosyltransferase. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane
CC {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 10 family.
CC {ECO:0000305}.
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DR EMBL; AJ535752; CAD59736.1; -; mRNA.
DR RefSeq; NP_989759.1; NM_204428.1.
DR AlphaFoldDB; Q8AWC7; -.
DR SMR; Q8AWC7; -.
DR STRING; 9031.ENSGALP00000008285; -.
DR CAZy; GT10; Glycosyltransferase Family 10.
DR PaxDb; Q8AWC7; -.
DR GeneID; 395071; -.
DR KEGG; gga:395071; -.
DR CTD; 170384; -.
DR VEuPathDB; HostDB:geneid_395071; -.
DR eggNOG; KOG2619; Eukaryota.
DR InParanoid; Q8AWC7; -.
DR OrthoDB; 551308at2759; -.
DR PhylomeDB; Q8AWC7; -.
DR UniPathway; UPA00378; -.
DR PRO; PR:Q8AWC7; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0036065; P:fucosylation; IBA:GO_Central.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.11660; -; 1.
DR InterPro; IPR017176; Alpha-1_3-FUT_met.
DR InterPro; IPR031481; Glyco_tran_10_N.
DR InterPro; IPR001503; Glyco_trans_10.
DR InterPro; IPR038577; GT10-like_C_sf.
DR PANTHER; PTHR11929; PTHR11929; 1.
DR Pfam; PF17039; Glyco_tran_10_N; 1.
DR Pfam; PF00852; Glyco_transf_10; 1.
DR PIRSF; PIRSF037332; Alpha1_3FUT_met; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Glycoprotein; Glycosyltransferase; Golgi apparatus;
KW Membrane; Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..505
FT /note="Alpha-(1,3)-fucosyltransferase 11"
FT /id="PRO_0000299012"
FT TOPO_DOM 1..12
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 13..29
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 30..505
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT REGION 30..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 79
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 178
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 330
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 483
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 110..115
FT /evidence="ECO:0000250"
FT DISULFID 401..404
FT /evidence="ECO:0000250"
SQ SEQUENCE 505 AA; 57516 MW; CA5102A0537B37F6 CRC64;
MGGGGPGRAA RRGPTCLWVT LALAWGAGSR AAAGDGDGDG EPGPGDAGTP CGAEGWARAA
VPPGPAFVAA ASYRGPGNND TRSNKALPIL LWWSGSLFPH FPGDTERIDC PRGSCLVTRS
RRAARHRRTK ALIFYGTDFR AYEAPLPRLP HQTWALFHEE SPMNNYLLSH PPGIRLFNYT
ATFRRESDYP LTLQWLPGAG YLRGPALPLA EKDAWRRRGY GPVLYMQSHC DVPSDRDRYV
RELMKYIQVD SYGKCLHNRE LPSERLRDTS TATTEDPEFM AFIARYKFHL ALENAICNDY
MTEKLWRPMH LGAVPVYRGS PAVRDWMPNN LSIILIDDFD SPQELAKYLD FLDKNGEEYM
KYLEYKNLDG IKNQFLLESL ERREWGVNDM TLPNYLNGFE CFICDRENAR VRAEQEHKKS
RGKTPAPSPH IAHFQHMGCP MPTPGFGSVE DLPGEDSWKE MWLQDYWQSL DQGEALTAMI
RHNESHQGRF WDYMHEIFLK RTRQH
