ID   FUT11_ORYLA             Reviewed;         497 AA.
AC   Q5F2N2;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Alpha-(1,3)-fucosyltransferase 11;
DE            EC=2.4.1.-;
DE   AltName: Full=Fucosyltransferase XI;
DE            Short=Fuc-TXI;
DE            Short=FucT-XI;
DE   AltName: Full=Galactoside 3-L-fucosyltransferase 11;
DE            Short=Fucosyltransferase 11;
GN   Name=fut11;
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=8090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Martinez-Duncker I., Oriol R., Mollicone R.;
RT   "Phylogeny of fucosyltransferases.";
RL   Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable fucosyltransferase. {ECO:0000250}.
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane
CC       {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 10 family.
CC       {ECO:0000305}.
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DR   EMBL; AJ879587; CAI52077.1; -; mRNA.
DR   RefSeq; NP_001098247.1; NM_001104777.1.
DR   AlphaFoldDB; Q5F2N2; -.
DR   STRING; 8090.ENSORLP00000008041; -.
DR   CAZy; GT10; Glycosyltransferase Family 10.
DR   PRIDE; Q5F2N2; -.
DR   Ensembl; ENSORLT00000042718; ENSORLP00000039427; ENSORLG00000006402.
DR   GeneID; 100049386; -.
DR   KEGG; ola:100049386; -.
DR   CTD; 170384; -.
DR   eggNOG; KOG2619; Eukaryota.
DR   GeneTree; ENSGT00940000158983; -.
DR   InParanoid; Q5F2N2; -.
DR   OrthoDB; 551308at2759; -.
DR   UniPathway; UPA00378; -.
DR   Proteomes; UP000001038; Chromosome 10.
DR   Proteomes; UP000265180; Unplaced.
DR   Proteomes; UP000265200; Unplaced.
DR   Bgee; ENSORLG00000006402; Expressed in gastrula and 13 other tissues.
DR   GO; GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0036065; P:fucosylation; IBA:GO_Central.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.11660; -; 1.
DR   InterPro; IPR017176; Alpha-1_3-FUT_met.
DR   InterPro; IPR031481; Glyco_tran_10_N.
DR   InterPro; IPR001503; Glyco_trans_10.
DR   InterPro; IPR038577; GT10-like_C_sf.
DR   PANTHER; PTHR11929; PTHR11929; 1.
DR   Pfam; PF17039; Glyco_tran_10_N; 1.
DR   Pfam; PF00852; Glyco_transf_10; 1.
DR   PIRSF; PIRSF037332; Alpha1_3FUT_met; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Glycosyltransferase; Golgi apparatus;
KW   Membrane; Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..497
FT                   /note="Alpha-(1,3)-fucosyltransferase 11"
FT                   /id="PRO_0000299015"
FT   TOPO_DOM        1..6
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        7..27
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        28..497
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   REGION          406..427
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        169
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        474
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        101..106
FT                   /evidence="ECO:0000250"
FT   DISULFID        392..395
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   497 AA;  57187 MW;  7E1DBF87B4B772EF CRC64;
     MACRRRLLPC AGLGLFGVLC WVWVSFASFP DDQLPLEVFD TVDRGAFLPQ SAFREMEFAS
     IASYKGPGNT DGRSNKQLPI LLWWSAGLFP HFPGDTERID CALSSCLVTS NRKVQLYKRT
     ASIIFYGTDF RAYEAPLPRL PHQTWALFHE ESPMNNYFLS HAPGIRLFNY TATFRRESDY
     PLTLQWLPSL DYLLRPVAVS LEEKNRLRRE GMAPVLYMQS HCDVPSDRDR YVQELMKYIQ
     VDSYGKCLKN KPLPEHLEDT ATATGEEPGF MNFVARYKFH LAFENGLCPD YMTEKLWRPL
     HQGCVPVYRG SPAVADWMPN GHAAIIIDNF PSPKALADFL RHLDENDDEY TRYLEFKNLK
     SITNTRLLEA LETREWGVND MSKPNYLNGF ECYVCDQENA RLAAERAHRK DPERNPPPLP
     KMASNSHMGC PLPSPGYGQV QDLPADDGWL QIWPQDYWQS LDQAEGLESL IRHNESDPSL
     LWRHIQSITE RRARGKH