ID   FUT11_XENTR             Reviewed;         533 AA.
AC   Q6A1G2;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Alpha-(1,3)-fucosyltransferase 11;
DE            EC=2.4.1.-;
DE   AltName: Full=Fucosyltransferase XI;
DE            Short=Fuc-TXI;
DE            Short=FucT-XI;
DE   AltName: Full=Galactoside 3-L-fucosyltransferase 11;
DE            Short=Fucosyltransferase 11;
GN   Name=fut11;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Martinez-Duncker I., Oriol R., Mollicone R.;
RT   "Phylogeny of fucosyltransferases.";
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable fucosyltransferase. {ECO:0000250}.
CC   -!- PATHWAY: Protein modification; protein glycosylation.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane
CC       {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 10 family.
CC       {ECO:0000305}.
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DR   EMBL; AJ784816; CAH04945.1; -; mRNA.
DR   RefSeq; NP_001002904.1; NM_001002904.2.
DR   AlphaFoldDB; Q6A1G2; -.
DR   CAZy; GT10; Glycosyltransferase Family 10.
DR   PaxDb; Q6A1G2; -.
DR   Ensembl; ENSXETT00000033891; ENSXETP00000033891; ENSXETG00000015541.
DR   GeneID; 444888; -.
DR   KEGG; xtr:444888; -.
DR   CTD; 170384; -.
DR   Xenbase; XB-GENE-5933996; fut11.
DR   eggNOG; KOG2619; Eukaryota.
DR   HOGENOM; CLU_032075_0_1_1; -.
DR   InParanoid; Q6A1G2; -.
DR   OMA; ERIDCPR; -.
DR   OrthoDB; 551308at2759; -.
DR   PhylomeDB; Q6A1G2; -.
DR   TreeFam; TF316348; -.
DR   Reactome; R-XTR-9037629; Lewis blood group biosynthesis.
DR   UniPathway; UPA00378; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000015541; Expressed in heart and 12 other tissues.
DR   ExpressionAtlas; Q6A1G2; baseline.
DR   GO; GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046920; F:alpha-(1->3)-fucosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0036065; P:fucosylation; IBA:GO_Central.
DR   GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.11660; -; 1.
DR   InterPro; IPR017176; Alpha-1_3-FUT_met.
DR   InterPro; IPR031481; Glyco_tran_10_N.
DR   InterPro; IPR001503; Glyco_trans_10.
DR   InterPro; IPR038577; GT10-like_C_sf.
DR   PANTHER; PTHR11929; PTHR11929; 1.
DR   Pfam; PF17039; Glyco_tran_10_N; 1.
DR   Pfam; PF00852; Glyco_transf_10; 1.
DR   PIRSF; PIRSF037332; Alpha1_3FUT_met; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Glycosyltransferase; Golgi apparatus;
KW   Membrane; Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..533
FT                   /note="Alpha-(1,3)-fucosyltransferase 11"
FT                   /id="PRO_0000299016"
FT   TOPO_DOM        1..20
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        21..37
FT                   /note="Helical; Signal-anchor for type II membrane protein"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        38..533
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        148
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        206
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        358
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        511
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        138..143
FT                   /evidence="ECO:0000250"
FT   DISULFID        429..432
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   533 AA;  61023 MW;  F1A9AD0761345701 CRC64;
     MSAGCTQLVW GGRLHWGASH LLSCLLALCA LWVLAAAEPT EGGSANVQGV GEAALYQGRG
     QHRVPSEDNV AVLSDQWEPS SFQPSSAFSG TDLGTMVADS YRGPGNSDRR SNKELPILLW
     WSENLFPHFP GDAERIDCPL SSCMVTKNKS VKLHKRTKSI IFYGTDFRAY EAPLPRLPHQ
     TWALFHEESP MNNYVLSHLP GIRLFNYTAT FSRESDYPLT LQWLPTIGYL HNPALSMAEK
     NRWRKNGYAP VLYMQSHCDV PSDRDRYVKE LMKHLEIDSY GQCMKNREHP NKRLEDTSTA
     TTEDPEFMAF TARYKFHLAM ENAICADYMT EKLWRPMHLG AIPIYRGSPS VRDWMPNNHS
     IIMIDDFASP KELAEFIMTL DSDDEQYLKY LEYKKPGGTT NTFLLSSMEK REWGVNDMTA
     PNYLNGFECF VCDKENSRIK AEKTYKKSQQ GGAAPEPHIA DFNHMGCPMP TPGFGSAQEI
     PESDSWKQMW LQDYWQSFDQ GEALTAMIQR NETNQDRFWD YMHETYIKRS MNH