FUT8_ARATH
ID FUT8_ARATH Reviewed; 516 AA.
AC Q9XI78;
DT 05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT 31-MAY-2011, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Probable fucosyltransferase 8;
DE Short=AtFUT8;
DE EC=2.4.1.-;
GN Name=FUT8; OrderedLocusNames=At1g14100; ORFNames=F7A19.18;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP IDENTIFICATION AS A PUTATIVE FUCOSYLTRANSFERASE, AND TISSUE SPECIFICITY.
RX PubMed=11743104; DOI=10.1104/pp.010596;
RA Sarria R., Wagner T.A., O'Neill M.A., Faik A., Wilkerson C.G., Keegstra K.,
RA Raikhel N.V.;
RT "Characterization of a family of Arabidopsis genes related to xyloglucan
RT fucosyltransferase1.";
RL Plant Physiol. 127:1595-1606(2001).
CC -!- FUNCTION: May be involved in cell wall biosynthesis. May act as a
CC fucosyltransferase.
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane
CC {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
CC Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in leaves and stems.
CC {ECO:0000269|PubMed:11743104}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 37 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD39294.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC007576; AAD39294.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE29106.1; -; Genomic_DNA.
DR PIR; D86274; D86274.
DR RefSeq; NP_001077531.1; NM_001084062.1.
DR AlphaFoldDB; Q9XI78; -.
DR SMR; Q9XI78; -.
DR STRING; 3702.AT1G14100.1; -.
DR CAZy; GT37; Glycosyltransferase Family 37.
DR PaxDb; Q9XI78; -.
DR PRIDE; Q9XI78; -.
DR EnsemblPlants; AT1G14100.1; AT1G14100.1; AT1G14100.
DR GeneID; 5007694; -.
DR Gramene; AT1G14100.1; AT1G14100.1; AT1G14100.
DR KEGG; ath:AT1G14100; -.
DR Araport; AT1G14100; -.
DR TAIR; locus:2035812; AT1G14100.
DR eggNOG; ENOG502SC60; Eukaryota.
DR HOGENOM; CLU_001992_2_1_1; -.
DR InParanoid; Q9XI78; -.
DR OMA; PWLVFNS; -.
DR OrthoDB; 364119at2759; -.
DR BioCyc; ARA:AT1G14100-MON; -.
DR UniPathway; UPA00378; -.
DR PRO; PR:Q9XI78; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9XI78; baseline and differential.
DR Genevisible; Q9XI78; AT.
DR GO; GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008417; F:fucosyltransferase activity; IBA:GO_Central.
DR GO; GO:0008107; F:galactoside 2-alpha-L-fucosyltransferase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR GO; GO:0009969; P:xyloglucan biosynthetic process; IBA:GO_Central.
DR InterPro; IPR004938; XG_FTase.
DR PANTHER; PTHR31889; PTHR31889; 1.
DR Pfam; PF03254; XG_FTase; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycoprotein; Glycosyltransferase;
KW Golgi apparatus; Membrane; Reference proteome; Signal-anchor; Transferase;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..516
FT /note="Probable fucosyltransferase 8"
FT /id="PRO_0000193917"
FT TRANSMEM 5..25
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 26..516
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT CARBOHYD 35
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 116
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 211
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 362
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 463
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 516 AA; 59286 MW; 72E2C96AC88EECDE CRC64;
MKVVITVVTC LFLLSVMQLS FFNIFNYQLL DATTNGSKDS RKSKDKLLGG LLTADFDEDS
CLSRYESSLY RKPSPYKPSR YLVSKLRSYE MLHKRCGPGT EAYKKATEIL GHDDENHSTK
SVGECRYIVW IAVYGLGNRI LTLASLFLYA LLTDRIMLVD QRTDISDLFC EPFPGTSWLL
PLDFPLTDQL DSFNKESPRC YGTMLKNHAI NSTTTESIIP SYLCLYLIHD YDDYDKMFFC
ESDQILIRQV PWLVFNSNLY FIPSLWLIPS FQSELSKLFP QKETVFHHLA RYLFHPTNQV
WGMITRSYNG YLSRADERLG IQVRVFSKPA GYFQHVMDQI LACTQREKLL PEVFVLETQV
TNTSRSSKLK AVLVTSLYPE YSEILRQMYW KGPSSTGEII QIYQPSQEIY QQTDNKLHDQ
KALAEIYLLS LTDYIVTSDS STFGYVAQGL GGLKPWILYK PKNHTAPEPP CVRAVSMEPC
FLRAPLYGCQ AKKVNITPFV MYCEDRITGL KLVDSN
