ID   FXYD6_MACFA             Reviewed;          95 AA.
AC   Q4R566;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=FXYD domain-containing ion transport regulator 6;
DE   AltName: Full=Phosphohippolin;
DE   Flags: Precursor;
GN   Name=FXYD6; ORFNames=QccE-17168;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FXYD family. {ECO:0000305}.
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DR   EMBL; AB169678; BAE01759.1; -; mRNA.
DR   RefSeq; NP_001272194.1; NM_001285265.1.
DR   AlphaFoldDB; Q4R566; -.
DR   SMR; Q4R566; -.
DR   STRING; 9541.XP_005579829.1; -.
DR   GeneID; 101867245; -.
DR   CTD; 53826; -.
DR   eggNOG; ENOG502S570; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0099106; F:ion channel regulator activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0043269; P:regulation of ion transport; IEA:InterPro.
DR   InterPro; IPR000272; Ion-transport_regulator_FXYD.
DR   Pfam; PF02038; ATP1G1_PLM_MAT8; 1.
DR   PROSITE; PS01310; FXYD; 1.
PE   3: Inferred from homology;
KW   Ion channel; Ion transport; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix; Transport.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000250|UniProtKB:Q91XV6"
FT   CHAIN           19..95
FT                   /note="FXYD domain-containing ion transport regulator 6"
FT                   /id="PRO_0000010373"
FT   TOPO_DOM        19..35
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        59..95
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   95 AA;  10572 MW;  3EB83156B52532DF CRC64;
     MELVLVFLCS LLAPMVLAST AEKEKEMDPF HYDYQTLRIG GLVFAVVLFS VGILLILSRR
     CKCSFNQKPR APGDEEAQVE NLITANATEP QKAEN