ID   FXYD6_PONAB             Reviewed;          95 AA.
AC   Q5RB29;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=FXYD domain-containing ion transport regulator 6;
DE   AltName: Full=Phosphohippolin;
DE   Flags: Precursor;
GN   Name=FXYD6;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FXYD family. {ECO:0000305}.
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DR   EMBL; CR858829; CAH91031.1; -; mRNA.
DR   RefSeq; NP_001125596.1; NM_001132124.1.
DR   AlphaFoldDB; Q5RB29; -.
DR   SMR; Q5RB29; -.
DR   STRING; 9601.ENSPPYP00000004489; -.
DR   Ensembl; ENSPPYT00000004665; ENSPPYP00000004489; ENSPPYG00000003918.
DR   GeneID; 100172512; -.
DR   KEGG; pon:100172512; -.
DR   CTD; 53826; -.
DR   eggNOG; ENOG502S570; Eukaryota.
DR   GeneTree; ENSGT00940000153062; -.
DR   InParanoid; Q5RB29; -.
DR   OrthoDB; 1524217at2759; -.
DR   Proteomes; UP000001595; Chromosome 11.
DR   GO; GO:0098978; C:glutamatergic synapse; IEA:Ensembl.
DR   GO; GO:0099055; C:integral component of postsynaptic membrane; IEA:Ensembl.
DR   GO; GO:0099056; C:integral component of presynaptic membrane; IEA:Ensembl.
DR   GO; GO:0099106; F:ion channel regulator activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0043269; P:regulation of ion transport; IEA:InterPro.
DR   InterPro; IPR000272; Ion-transport_regulator_FXYD.
DR   Pfam; PF02038; ATP1G1_PLM_MAT8; 1.
DR   PROSITE; PS01310; FXYD; 1.
PE   3: Inferred from homology;
KW   Ion channel; Ion transport; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix; Transport.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000250|UniProtKB:Q91XV6"
FT   CHAIN           19..95
FT                   /note="FXYD domain-containing ion transport regulator 6"
FT                   /id="PRO_0000010375"
FT   TOPO_DOM        19..35
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        59..95
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   95 AA;  10512 MW;  2DAD76A40163D2CE CRC64;
     MELVLVFLCS LLAPTVLASA AEKEKEMDPF HYDYQTLRIG GLVFAVVLFS VGILLILSRR
     CKCSFNQKPR APGDEEAQVE NLITANATEP QKAEN