FXYD7_RAT
ID FXYD7_RAT Reviewed; 80 AA.
AC P59649;
DT 30-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 30-APR-2003, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=FXYD domain-containing ion transport regulator 7;
GN Name=Fxyd7;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Lee N.H., Glodek A., Chandra I., Mason T.M., Quackenbush J.,
RA Kerlavage A.R., Adams M.D.;
RL Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP PROTEIN SEQUENCE OF 54-64 AND 68-80, AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RC STRAIN=Sprague-Dawley; TISSUE=Brain;
RA Lubec G., Kang S.U., Lubec S.;
RL Submitted (SEP-2007) to UniProtKB.
RN [3]
RP RECONSTRUCTION FROM ESTS, AND CONCEPTUAL TRANSLATION.
RX PubMed=10950925; DOI=10.1006/geno.2000.6274;
RA Sweadner K.J., Rael E.;
RT "The FXYD gene family of small ion transport regulators or channels: cDNA
RT sequence, protein signature sequence, and expression.";
RL Genomics 68:41-56(2000).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-73, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22673903; DOI=10.1038/ncomms1871;
RA Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA Olsen J.V.;
RT "Quantitative maps of protein phosphorylation sites across 14 different rat
RT organs and tissues.";
RL Nat. Commun. 3:876-876(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FXYD family. {ECO:0000305}.
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DR EMBL; AW914994; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_071291.1; NM_022008.1.
DR AlphaFoldDB; P59649; -.
DR SMR; P59649; -.
DR STRING; 10116.ENSRNOP00000028603; -.
DR iPTMnet; P59649; -.
DR PhosphoSitePlus; P59649; -.
DR SwissPalm; P59649; -.
DR PaxDb; P59649; -.
DR PRIDE; P59649; -.
DR GeneID; 63848; -.
DR KEGG; rno:63848; -.
DR UCSC; RGD:620830; rat.
DR CTD; 53822; -.
DR RGD; 620830; Fxyd7.
DR VEuPathDB; HostDB:ENSRNOG00000021067; -.
DR eggNOG; ENOG502SFZR; Eukaryota.
DR HOGENOM; CLU_168385_1_0_1; -.
DR InParanoid; P59649; -.
DR OMA; SKCNPFL; -.
DR OrthoDB; 1630491at2759; -.
DR PhylomeDB; P59649; -.
DR TreeFam; TF333443; -.
DR Reactome; R-RNO-5578775; Ion homeostasis.
DR Reactome; R-RNO-936837; Ion transport by P-type ATPases.
DR PRO; PR:P59649; -.
DR Proteomes; UP000002494; Chromosome 1.
DR Bgee; ENSRNOG00000021067; Expressed in cerebellum and 20 other tissues.
DR Genevisible; P59649; RN.
DR GO; GO:0016021; C:integral component of membrane; TAS:RGD.
DR GO; GO:0051117; F:ATPase binding; IPI:RGD.
DR GO; GO:0099106; F:ion channel regulator activity; IEA:InterPro.
DR GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR GO; GO:0043269; P:regulation of ion transport; IDA:RGD.
DR InterPro; IPR000272; Ion-transport_regulator_FXYD.
DR Pfam; PF02038; ATP1G1_PLM_MAT8; 1.
DR PROSITE; PS01310; FXYD; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Ion channel; Ion transport; Membrane;
KW Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..80
FT /note="FXYD domain-containing ion transport regulator 7"
FT /id="PRO_0000148192"
FT TRANSMEM 23..45
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 56..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 73
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:22673903"
SQ SEQUENCE 80 AA; 8487 MW; 135CEB3EC0D06CDC CRC64;
MATPTQSPTN VPEETDPFFY DYATVQTVGM TLATIMFVLG IIIIISKKVK CRKADSRSES
PTCKSCKSEL PSSAPGGGGV
