ID   FYV10_CANAL             Reviewed;         572 AA.
AC   Q5A4G9; A0A1D8PKG6;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Protein FYV10;
GN   Name=FYV10; OrderedLocusNames=CAALFM_C305850WA; ORFNames=CaO19.7365;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Involved in the proteasome-dependent degradation of fructose-
CC       1,6-bisphosphatase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FYV10 family. {ECO:0000305}.
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DR   EMBL; CP017625; AOW28593.1; -; Genomic_DNA.
DR   RefSeq; XP_716606.1; XM_711513.1.
DR   AlphaFoldDB; Q5A4G9; -.
DR   SMR; Q5A4G9; -.
DR   STRING; 237561.Q5A4G9; -.
DR   PRIDE; Q5A4G9; -.
DR   GeneID; 3641758; -.
DR   KEGG; cal:CAALFM_C305850WA; -.
DR   CGD; CAL0000193350; orf19.7365.
DR   VEuPathDB; FungiDB:C3_05850W_A; -.
DR   eggNOG; KOG0396; Eukaryota.
DR   HOGENOM; CLU_027445_2_0_1; -.
DR   InParanoid; Q5A4G9; -.
DR   OMA; DVKYDEW; -.
DR   OrthoDB; 1087488at2759; -.
DR   Proteomes; UP000000559; Chromosome 3.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0034657; C:GID complex; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; IEA:UniProt.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   InterPro; IPR024964; CTLH/CRA.
DR   InterPro; IPR006595; CTLH_C.
DR   InterPro; IPR027714; Fyv10/MAEA.
DR   InterPro; IPR045098; Fyv10_fam.
DR   InterPro; IPR044063; ZF_RING_GID.
DR   PANTHER; PTHR12170; PTHR12170; 1.
DR   PANTHER; PTHR12170:SF2; PTHR12170:SF2; 1.
DR   Pfam; PF10607; CLTH; 1.
DR   PROSITE; PS51867; ZF_RING_GID; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..572
FT                   /note="Protein FYV10"
FT                   /id="PRO_0000292454"
FT   DOMAIN          210..268
FT                   /note="CTLH"
FT   ZN_FING         491..557
FT                   /note="RING-Gid-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01215"
FT   REGION          110..142
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        110..139
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   572 AA;  66107 MW;  D83BB1BA876EBF4D CRC64;
     MTEPTLNFHI QTHQNQFKIP HELIKKNFKL IQKLIEKQRK QLIDDISKIK KCKTTSPSFK
     LELIQKLIKN FESFMKKLQN FINKDEEFRS RLIARLENLT ELQQYVITNN DNQEGQNHEE
     STENNNNNRN NNNNSTTTDD DKLLDFHNPN LINWYRDQTN LLIVDYLIKS NTRTRFEDNG
     EDNPGNIGLL LLKNLTKTNP KLLKLIDYDL LENFNKVFVS IINNHDLSLI VGWFNENKNL
     LNKINSNLEF EINYCKFLTL IEKGDINEAI NYSRENLSGY GNKENYQQTN NNNNNTFSNG
     DTTSTNHLTN LERLKGLGGL LVFRSMENNN KNNNDLNSND TPLSSKLMLN STPFKEYQKL
     LSNERWESLA QCFIENFTKL YGISKNFPIY IYLSAGLSSL KTKSCYHNVE NTIFKHSTGN
     GIDYDNGNDD YDDDDDDDDE GGVIDSNLSF ISAETTTNTN TTSNSGKSLL NDPKYRGPNH
     YYKLLNKINN CPICSPELFK LSQNLPYAQL ITSIFNNPFK LPNGNIYPFD KLLAPTDKYL
     SEKNTLLRAN KVKDPLTREI FTIDSCIRVF PA