ID   FYV10_CANGA             Reviewed;         488 AA.
AC   Q6FTG6;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Protein FYV10;
GN   Name=FYV10; OrderedLocusNames=CAGL0G02651g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in the proteasome-dependent degradation of fructose-
CC       1,6-bisphosphatase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FYV10 family. {ECO:0000305}.
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DR   EMBL; CR380953; CAG59405.1; -; Genomic_DNA.
DR   RefSeq; XP_446478.1; XM_446478.1.
DR   AlphaFoldDB; Q6FTG6; -.
DR   SMR; Q6FTG6; -.
DR   STRING; 5478.XP_446478.1; -.
DR   EnsemblFungi; CAG59405; CAG59405; CAGL0G02651g.
DR   GeneID; 2888366; -.
DR   KEGG; cgr:CAGL0G02651g; -.
DR   CGD; CAL0130701; CAGL0G02651g.
DR   VEuPathDB; FungiDB:CAGL0G02651g; -.
DR   eggNOG; KOG0396; Eukaryota.
DR   HOGENOM; CLU_027445_2_0_1; -.
DR   InParanoid; Q6FTG6; -.
DR   Proteomes; UP000002428; Chromosome G.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0034657; C:GID complex; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:EnsemblFungi.
DR   GO; GO:0043066; P:negative regulation of apoptotic process; IEA:EnsemblFungi.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; IEA:EnsemblFungi.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:EnsemblFungi.
DR   InterPro; IPR024964; CTLH/CRA.
DR   InterPro; IPR006595; CTLH_C.
DR   InterPro; IPR027714; Fyv10/MAEA.
DR   InterPro; IPR045098; Fyv10_fam.
DR   InterPro; IPR044063; ZF_RING_GID.
DR   PANTHER; PTHR12170; PTHR12170; 1.
DR   PANTHER; PTHR12170:SF2; PTHR12170:SF2; 1.
DR   Pfam; PF10607; CLTH; 1.
DR   SMART; SM00668; CTLH; 1.
DR   PROSITE; PS50897; CTLH; 1.
DR   PROSITE; PS51867; ZF_RING_GID; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..488
FT                   /note="Protein FYV10"
FT                   /id="PRO_0000292455"
FT   DOMAIN          175..233
FT                   /note="CTLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00058"
FT   ZN_FING         406..473
FT                   /note="RING-Gid-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01215"
SQ   SEQUENCE   488 AA;  56784 MW;  A565205A01AB20B3 CRC64;
     MAETTSLINE PDVDFHLKLN QHSFNIPYEQ LQRNSRYLNR LIEKEIDELN SHYERLNIAL
     GSGNIEGDKK ALQELKDIIR SVEIFEKRLQ KRVNEEVPIL KRLEVRINFF KELENAKQQV
     ADITPLMEWY LKFTNILIGD YLTRHTTSNS SPELGLPGVT FLEQEGIQDL LDTDILLTGN
     RISTALVDNH DLRPLLDWIN DSKSYLKKNG SRLEFEARFQ QYIELLKASE YEEAIKCFQD
     YLLKFVNTNF NELTHASGLL LSINYCKEIM KAKASERSAI LTKDDGNPLE NEIRAYKYFF
     HKKPKIVEQQ HVKPVDLSYM NLSQNTDFEK YMLLLDDKRW GLLNELFLKD YYSLYGISQN
     DPLLIYLSLG ISTLKTRECL HHRRVAKSSS PLVDKKVEEE VLQNSCPVCD KTFAPIAESL
     PFAHHTQSQL FDDPIMLPNG NIYEAKRLKR LAKYLVDIKA IELGETEVID PIDKQIYNEA
     DFITMYPT