ID   FYV10_CHAGB             Reviewed;         441 AA.
AC   Q2H991;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Protein FYV10;
GN   Name=FYV10; ORFNames=CHGG_03213;
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS   NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=306901;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX   PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
CC   -!- FUNCTION: Involved in the proteasome-dependent degradation of fructose-
CC       1,6-bisphosphatase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FYV10 family. {ECO:0000305}.
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DR   EMBL; CH408030; EAQ91278.1; -; Genomic_DNA.
DR   RefSeq; XP_001229729.1; XM_001229728.1.
DR   AlphaFoldDB; Q2H991; -.
DR   SMR; Q2H991; -.
DR   STRING; 38033.XP_001229729.1; -.
DR   EnsemblFungi; EAQ91278; EAQ91278; CHGG_03213.
DR   GeneID; 4389687; -.
DR   eggNOG; KOG0396; Eukaryota.
DR   HOGENOM; CLU_027445_2_0_1; -.
DR   InParanoid; Q2H991; -.
DR   OMA; DVKYDEW; -.
DR   OrthoDB; 1087488at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; IEA:UniProt.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   InterPro; IPR013144; CRA_dom.
DR   InterPro; IPR024964; CTLH/CRA.
DR   InterPro; IPR006595; CTLH_C.
DR   InterPro; IPR027714; Fyv10/MAEA.
DR   InterPro; IPR045098; Fyv10_fam.
DR   InterPro; IPR006594; LisH.
DR   InterPro; IPR044063; ZF_RING_GID.
DR   PANTHER; PTHR12170; PTHR12170; 1.
DR   PANTHER; PTHR12170:SF2; PTHR12170:SF2; 1.
DR   Pfam; PF10607; CLTH; 1.
DR   SMART; SM00757; CRA; 1.
DR   SMART; SM00668; CTLH; 1.
DR   PROSITE; PS50897; CTLH; 1.
DR   PROSITE; PS50896; LISH; 1.
DR   PROSITE; PS51867; ZF_RING_GID; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..441
FT                   /note="Protein FYV10"
FT                   /id="PRO_0000292456"
FT   DOMAIN          125..157
FT                   /note="LisH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00126"
FT   DOMAIN          163..220
FT                   /note="CTLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00058"
FT   ZN_FING         364..426
FT                   /note="RING-Gid-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01215"
FT   REGION          312..354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        337..354
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   441 AA;  49130 MW;  05477878D2E86B96 CRC64;
     MADLEAANIN HDNHLLLDQP CLRLPYELLR KNFRSVHYPF EWDSTSVKNV VKETANGLIS
     GKASPQDAVE NLDQMLVKMR GLKRKLTAAA KEEDRLYRQM DSRVAHLREL ADLHTVDDVR
     YEAWSRQRLD RLLVDYMLRH GYDSSAIALA DERGMRDLVD IDTFVVMSRI RKSLEGGSVQ
     EALNWCNENK KELRKMQSNL EFLLRCQQYI EMMRTDSPAK MAEAIHHARK YITPFTETYP
     VEISSIAGLL AYRPGTISEP YASLYSASRW QKLADTFVEA HLKLLGLPMT PLLHIALSSG
     LSALKTPACH STQLQVPTQP EESQPVNGAG DGAATATAAA ASSTTSTAIP HHHHGTASLT
     TRVCPICSTE LNALARSVRY AHHGKSRLLE QDLVLLPNGR VYGKARLDEY AAKSGLPAGQ
     IKDLVTGEVF SGEEGRKVFV T