ID   FYV12_YEAST             Reviewed;         129 AA.
AC   Q08559; D6W2N9;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Protein FYV12;
DE   AltName: Full=Function required for yeast viability protein 12;
GN   Name=FYV12; OrderedLocusNames=YOR183W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169874;
RA   Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA   Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA   Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA   Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA   Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA   Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA   Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA   Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA   Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA   Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA   Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA   Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA   Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA   Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA   Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA   Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA   Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL   Nature 387:98-102(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   FUNCTION.
RX   PubMed=12663529; DOI=10.1093/genetics/163.3.875;
RA   Page N., Gerard-Vincent M., Menard P., Beaulieu M., Azuma M.,
RA   Dijkgraaf G.J.P., Li H., Marcoux J., Nguyen T., Dowse T., Sdicu A.-M.,
RA   Bussey H.;
RT   "A Saccharomyces cerevisiae genome-wide mutant screen for altered
RT   sensitivity to K1 killer toxin.";
RL   Genetics 163:875-894(2003).
CC   -!- FUNCTION: Involved in K1 killer toxin resistance.
CC       {ECO:0000269|PubMed:12663529}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; Z75091; CAA99392.1; -; Genomic_DNA.
DR   EMBL; BK006948; DAA10955.1; -; Genomic_DNA.
DR   PIR; S67075; S67075.
DR   RefSeq; NP_014826.1; NM_001183602.1.
DR   AlphaFoldDB; Q08559; -.
DR   BioGRID; 34578; 149.
DR   STRING; 4932.YOR183W; -.
DR   PaxDb; Q08559; -.
DR   PRIDE; Q08559; -.
DR   EnsemblFungi; YOR183W_mRNA; YOR183W; YOR183W.
DR   GeneID; 854355; -.
DR   KEGG; sce:YOR183W; -.
DR   SGD; S000005709; FYV12.
DR   VEuPathDB; FungiDB:YOR183W; -.
DR   HOGENOM; CLU_1961302_0_0_1; -.
DR   BioCyc; YEAST:G3O-33694-MON; -.
DR   PRO; PR:Q08559; -.
DR   Proteomes; UP000002311; Chromosome XV.
DR   RNAct; Q08559; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..129
FT                   /note="Protein FYV12"
FT                   /id="PRO_0000239648"
FT   TRANSMEM        109..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        91
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   129 AA;  14792 MW;  31207AFE24895BFB CRC64;
     MRLLHHGEYG TKLIGGKCSI DGKLGHPCPL SRRRKKHLRE KEMGPQYVRM YGPKRKAIIR
     TGNPDDGINL PDTGRGTLTA ATIWSRAYHS NYSYLVRPKV VTLSKHRELM TTFLLYVLYV
     CIYISAFIK