G11A_ORYSI
ID G11A_ORYSI Reviewed; 589 AA.
AC A2YBX5; P47997; Q5Z583;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Protein kinase G11A;
DE EC=2.7.11.1;
GN ORFNames=OsI_021818;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 54-584.
RC STRAIN=cv. IR36; TISSUE=Leaf;
RX PubMed=2541432; DOI=10.1073/pnas.86.9.3140;
RA Lawton M.A., Yamamoto R.T., Hanks S.K., Lamb C.J.;
RT "Molecular cloning of plant transcripts encoding protein kinase homologs.";
RL Proc. Natl. Acad. Sci. U.S.A. 86:3140-3144(1989).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 327-434.
RC STRAIN=cv. IR36; TISSUE=Seedling;
RX PubMed=2026273; DOI=10.1016/0014-5793(91)80453-a;
RA Feng X.H., Kung S.D.;
RT "Diversity of the protein kinase gene family in rice.";
RL FEBS Lett. 282:98-102(1991).
CC -!- FUNCTION: May play a role in the regulation of metabolism and signal
CC transduction processes.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1;
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
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DR EMBL; CM000131; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; J04556; AAA33905.1; -; mRNA.
DR PIR; B30311; B30311.
DR AlphaFoldDB; A2YBX5; -.
DR SMR; A2YBX5; -.
DR STRING; 39946.A2YBX5; -.
DR PRIDE; A2YBX5; -.
DR Proteomes; UP000007015; Chromosome 6.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR Pfam; PF00069; Pkinase; 2.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Kinase; Nucleotide-binding; Reference proteome;
KW Serine/threonine-protein kinase; Transferase.
FT CHAIN 1..589
FT /note="Protein kinase G11A"
FT /id="PRO_0000300872"
FT DOMAIN 195..533
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT REGION 1..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 320
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT ECO:0000255|PROSITE-ProRule:PRU10027"
FT BINDING 201..209
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 224
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT CONFLICT 215
FT /note="N -> S (in Ref. 2; AAA33905)"
FT /evidence="ECO:0000305"
FT CONFLICT 218
FT /note="K -> E (in Ref. 2; AAA33905)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 589 AA; 64825 MW; E686A223D4DC60FF CRC64;
MASKAMPRAP PAAPNLQSLK LCSQNDSSLE TTSPSKRSAL VPGRSAESSK PNSEVVQKEQ
KSTQHQNESI DLTGSNDPAE VKAEGNLVPK RLADEEKGVV EDGIANGSLK SSSALGKEHG
IASASGSARL VGRSETGERG FSSSRCRPST SSDVSDESAC SSISSVTKPH KANDSRWEAI
QMIRTRDGIL GLSHFKLLKK LGCGDIGSVY LSELNGTKSY FAMKVMDKAS LASRKKLLRA
QTEKEILQCL DHPFLPTLYT HFETDKFSCL VMEFCPGGDL HTLRQRQRGK YFPEQAVKFY
VAEILLAMEY LHMLGIIYRD LKPENVLVRE DGHIMLSDFD LSLRCAVSPT LIRSSNPDAE
ALRKNNQAYC VQPACVEPSC MIQPSCATPT TCFGPRFFSK SKKDRKPKPE VVNQVSPWPE
LIAEPSDARS MSFVGTHEYL APEIIKGEGH GSAVDWWTFG IFLYELLFGK TPFKGSGNRA
TLFNVIGQPL RFPEYPVVSF SARDLIRGLL VKEPQQRLGC KRGATEIKQH PFFEGVNWAL
IRCASPPEVP RPVEIERPPK QPVSTSEPAA APSDAAQKSS DSYLEFDFF
