ID   G156_PARPR              Reviewed;        2715 AA.
AC   P13837;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   02-DEC-2020, entry version 77.
DE   RecName: Full=G surface protein, allelic form 156;
DE   Flags: Precursor;
GN   Name=156G;
OS   Paramecium primaurelia.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX   NCBI_TaxID=5886;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=156;
RX   PubMed=3783679; DOI=10.1016/0022-2836(86)90380-3;
RA   Prat A., Katinka M., Caron F., Meyer E.;
RT   "Nucleotide sequence of the Paramecium primaurelia G surface protein. A
RT   huge protein with a highly periodic structure.";
RL   J. Mol. Biol. 189:47-60(1986).
CC   -!- FUNCTION: This protein is the surface antigen or immobilization antigen
CC       of Paramecium primaurelia.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor.
CC   -!- INDUCTION: Expression of G protein occurs at low temperatures (14-32
CC       degrees Celsius).
CC   -!- DOMAIN: It has internal homologies and a highly periodic structure with
CC       34 periods of about 75 residues, each period containing 8 cysteines,
CC       except for four half periods. A variable part of 475 residues comprises
CC       4 almost identical periods in the middle of the protein.
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DR   EMBL; X03882; CAA27514.1; -; Genomic_DNA.
DR   PIR; A23475; A23475.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002895; Paramecium_SA.
DR   InterPro; IPR016201; PSI.
DR   Pfam; PF01508; Paramecium_SA; 31.
DR   SMART; SM00639; PSA; 33.
DR   SMART; SM00423; PSI; 10.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Membrane; Repeat;
KW   Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..2715
FT                   /note="G surface protein, allelic form 156"
FT                   /id="PRO_0000021310"
FT   REPEAT          111..171
FT                   /note="PSA 1"
FT   REPEAT          177..237
FT                   /note="PSA 2"
FT   REPEAT          243..303
FT                   /note="PSA 3"
FT   REPEAT          309..366
FT                   /note="PSA 4"
FT   REPEAT          372..404
FT                   /note="PSA 5"
FT   REPEAT          405..467
FT                   /note="PSA 6"
FT   REPEAT          473..530
FT                   /note="PSA 7"
FT   REPEAT          536..596
FT                   /note="PSA 8"
FT   REPEAT          602..673
FT                   /note="PSA 9"
FT   REPEAT          688..748
FT                   /note="PSA 10"
FT   REPEAT          752..812
FT                   /note="PSA 11"
FT   REPEAT          820..895
FT                   /note="PSA 12"
FT   REPEAT          934..1001
FT                   /note="PSA 13"
FT   REPEAT          1008..1067
FT                   /note="PSA 14"
FT   REPEAT          1073..1141
FT                   /note="PSA 15"
FT   REPEAT          1147..1215
FT                   /note="PSA 16"
FT   REPEAT          1221..1289
FT                   /note="PSA 17"
FT   REPEAT          1295..1363
FT                   /note="PSA 18"
FT   REPEAT          1369..1437
FT                   /note="PSA 19"
FT   REPEAT          1443..1507
FT                   /note="PSA 20"
FT   REPEAT          1513..1578
FT                   /note="PSA 21"
FT   REPEAT          1586..1652
FT                   /note="PSA 22"
FT   REPEAT          1693..1751
FT                   /note="PSA 23"
FT   REPEAT          1759..1819
FT                   /note="PSA 24"
FT   REPEAT          1827..1898
FT                   /note="PSA 25"
FT   REPEAT          1904..1976
FT                   /note="PSA 26"
FT   REPEAT          1984..2044
FT                   /note="PSA 27"
FT   REPEAT          2080..2149
FT                   /note="PSA 28"
FT   REPEAT          2155..2215
FT                   /note="PSA 29"
FT   REPEAT          2219..2286
FT                   /note="PSA 30"
FT   REPEAT          2290..2355
FT                   /note="PSA 31"
FT   REPEAT          2359..2430
FT                   /note="PSA 32"
FT   REPEAT          2434..2500
FT                   /note="PSA 33"
FT   REPEAT          2505..2573
FT                   /note="PSA 34"
SQ   SEQUENCE   2715 AA;  279551 MW;  97BE359AB9C7C298 CRC64;
     MNNKFIIFSL LLALVASQTY SLTSCTCAQL LSEGDCIKNV SLGCSWDTTK KTCGVSTTPV
     TPTVTYAAYC DTFAETDCPK AKPCTDCGNY AACAWVESKC TFFTGCTPFA KTLDSECQAI
     SNRCITDGTH CVEVDACSTY KKQLPCAKNA AGSLCYWDTT NNTCVDANTC DKLPATFATD
     KDCRDVISTC TTKTGGGCVD SGNNCSDQTL EIQCVWNKLK TTSCYWDGAA CKDRICDNAP
     TSLTTDDACK TFRTDGTCTT KANGGCVTRT TCAAATIQAS CIKNSSGGDC YWTGTACVDK
     ACANTPTTIA TNSACAGFVT GCITKSGGGC VVNGACSVAN VQAACVKNPS NFDCIWDTTC
     KEKTCANAST TNNTHDLCTS YLSTCTVKSG GGCQNRTCAN APTTMTTNDA CEAYFTGNNC
     ITKSGGGCVT NTTCAAITLE AACVKNSSGS TCFWDTASSS CKDKTCVNAP ATNTTHDLCQ
     PFLNTCTVNS TSAGCVEKTC ENSLVLAICD KDTSSRACIW KGKCYKKQCV LASSATTTHA
     DCQTYHSTCT LSNSGTGCVP LPLKCEAITI EAACNLKANG QPCGWNGSQC IDKACSTASK
     TFTTTSQCTG HISTCVANNP VTVNGSLTIQ GCQDLPTTCA RRKSSENCEI TRVGFPTCLW
     VSSSTSCVEK SCATASTVGT TGALSAGGFT FSGCQTYLNT CISNNTADGC IAKPSSCSSL
     VSSNCRDGSK ASGDCYWNGS SCVDKTCANI IQTTHNSCNT TFNQCTVNNG GTACQTLATA
     CTSYSTQENC KFTSTNKNCV WTGLACRNAT CADAPDTTAY DSDTECLAYP TPSETCTVVY
     KVGAQGCVSK SANCSDYMTS AQCHKTLTNL TANDDCKWIV DRCYALSSFA TGACTTFKGT
     KTMCEGYRAG CTNTVGAASS ASCTLDCTLK TGSGLTFADC QALDSTCSVK KDGTGCIAIQ
     STCAGYGSTA ANCFRSSASG TAGYCAMNTN CQSVTSAAEC AFVTGLTGLD HSKCQLYHSS
     CTSLKDGTGC QEYKTTCSGY AATNNCATSG QGKCFFDVEC LRFSNCASIT GTGLTTAICG
     TYDAGCVANV NGTACQEKLA TCDLYLTQNS CSTSAAAATA DKCAWSGTAC LAVTTVGTHC
     PYVTGTGLTD LICAAYNANC TANKAGTACQ EKKATCNLYT TEATCSTSAA AATADKCAWS
     GAACLAVTTV ATECAYVTGT GLTDLICAAY NANCTANKAG TACQEKKATC NLYTTEATCS
     TSAAAATADK CAWSGAACLA VTTVATECAY VTGTGLTNAI CAAYNANCTA NKAGTACQEK
     KATCNLYTTE ATCSTSAAAA TADKCAWSGA ACLAVTTVAT ECAYVTGTGL TNAICAAYNA
     NCTANKAGTA CQEKKATCNL YTTEATCSTS AAAATADKCA WSGAACLAVT TVATECAYVT
     GTGLTKAICA TYNAGCINLK DGTGCQEAKA NCKDYTTSNK CTAQTTSTLS CLWIDNSCYP
     VTDLNCSVIT GLGFVHAQCQ AYSTGCTSVS DGSKCQDFKS TCEQYPGTTL GCTKTASTKC
     YLQGSACITI SNVATDCAKI TGSAGTITFE ICQSYNTGCS VNRARSACVQ QQAQCSGYTS
     AMTSCYKSGA GLCIASTNTD TACVAATAAT CDAVYLGAGN YSSANCNEMK AGCTNNGTTA
     CVAKTCANAA GITFNHTNCN SYLNTCTVNS GNSACQTMAS KCADQTQASC LYSVEGECVV
     VGTSCVRKTC DTAATDATRD DDTECSTYQQ SCTVARLGAC QARAACATYK SSLQCKFNTS
     GGKCFWNPTN KTCVDLNCGN IEATTLYDTH NECVAVDATL ACTVRATNGA AAQGCMARGA
     CASYTIEEQC KTNASNGVCV WNTNANLPAP ACQDKSCTSA PTSTTTHNDC YAYYNTATVK
     CTVVATPSNS GGNPTLGGCQ QTAACSSYID KEQCQINANG DPCGWNGTQC ADKSCATASA
     TADYDDDTKC RAYITNKCTV SDSGQGCVEI PATCETMTQK QCYYNKAGDP CYWTGTACIT
     KSCDNAPDAT ATADECNTYL AGCTLNNVKC KTKVCEDFAF ATDALCKQAI STCTTNGTNC
     VTRGTCFQAL SQAGCVTSST NQQCEWIPAV LNASNVITSP AYCTIKNCST APITLTSEAA
     CAGYFTNCTT KNGGGCVTKS TCSAVTIDVA CTTALNGTVC AWDSAQNKCR DKDCQDFSGT
     THAACQAQRA GCTAGAGGKC ARVQNCEQTS VRAACIEGTN GPCLWIDKYQ NTDGTKGACF
     RYTSCKSLNW NNDSSCKWIS NKCTTNGSNC VGITLCSETN TDGGCVTGYD GACIQSVPDL
     NSSDPKVCKP YTSCADAFYT THSDCQIASS KCTTNGTTGC IALGSCSSYT VQAGCYFNDK
     GTLYTSGVIT STGICTWDTT SSSCRDQSCA DLTGTTHATC SSQLSTCTSD GTTCLLKGAC
     TSYTTQTACT TAVGSDGACY WELASATNNN TAKCRLLTCA DIQNGTATNV CSVALSTCVS
     NGTACIPKAN CSTYTSKVAC NSGGLDGICV FTQSTATGAA AGTGTCALMT ACTVANNDQT
     ACQAARDRCS WTAASGTRAT AVASKCATHT CATNQATNGA CTRFLNWDKK TQQVCTLVSG
     ACTATDPSSF SSNDCFLVSG YTYTCNASTS KCGVCTAVVV QPNTTDNNTN TTDNNTTTDS
     GYILGLSIVL GYLMF