G1L6_ORYSJ
ID G1L6_ORYSJ Reviewed; 248 AA.
AC Q6K5X1; A0A0P0VR07;
DT 19-FEB-2014, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Protein G1-like6 {ECO:0000303|PubMed:19901325};
DE Short=OsG1L6 {ECO:0000303|PubMed:19901325};
DE AltName: Full=Protein ABNORMAL FLOWER AND DWARF 1 {ECO:0000303|PubMed:26486996};
DE AltName: Full=Protein BEAK LIKE SPIKELET 1 {ECO:0000303|Ref.9};
DE AltName: Full=Protein BEAK-SHAPED GRAIN 1 {ECO:0000303|PubMed:23526395};
DE AltName: Full=Protein TRIANGULAR HULL 1 {ECO:0000303|PubMed:22203474};
GN Name=G1L6 {ECO:0000303|PubMed:19901325};
GN Synonyms=AFD1 {ECO:0000303|PubMed:26486996}, BLS1 {ECO:0000303|Ref.9},
GN BSG1 {ECO:0000303|PubMed:23526395}, TH1 {ECO:0000303|PubMed:22203474};
GN OrderedLocusNames=Os02g0811000 {ECO:0000312|EMBL:BAS81516.1},
GN LOC_Os02g56610 {ECO:0000305};
GN ORFNames=OJ1116_E04.14 {ECO:0000312|EMBL:BAD21590.1},
GN OsJ_08822 {ECO:0000312|EMBL:EAZ25035.1},
GN P0016F11.6 {ECO:0000312|EMBL:BAD22027.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Nipponbare;
RX PubMed=19901325; DOI=10.1073/pnas.0907896106;
RA Yoshida A., Suzaki Y., Tanaka W., Hirano H.-Y.;
RT "The homeotic gene long sterile lemma (G1) specifies sterile lemma identity
RT in the rice spikelet.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:20103-20108(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP DNA-BINDING, AND GENE FAMILY.
RX PubMed=23146749; DOI=10.1186/1745-6150-7-39;
RA Iyer L.M., Aravind L.;
RT "ALOG domains: provenance of plant homeotic and developmental regulators
RT from the DNA-binding domain of a novel class of DIRS1-type retroposons.";
RL Biol. Direct 7:39-39(2012).
RN [8]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=22203474; DOI=10.1007/s11103-011-9868-8;
RA Li X., Sun L., Tan L., Liu F., Zhu Z., Fu Y., Sun X., Sun X., Xie D.,
RA Sun C.;
RT "TH1, a DUF640 domain-like gene controls lemma and palea development in
RT rice.";
RL Plant Mol. Biol. 78:351-359(2012).
RN [9]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DISRUPTION
RP PHENOTYPE.
RX DOI=10.1007/s11105-012-0480-0;
RA Ma X., Cheng Z., Wu F., Jin M., Zhang L., Zhou F., Wang J., Zhou K., Ma J.,
RA Lin Q., Lei C., Wan J.;
RT "BEAK LIKE SPIKELET1 is required for lateral development of lemma and palea
RT in rice.";
RL Plant Mol. Biol. Rep. 31:98-108(2013).
RN [10]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=23526395; DOI=10.1007/s11427-013-4449-5;
RA Yan D., Zhou Y., Ye S., Zeng L., Zhang X., He Z.;
RT "Beak-shaped grain 1/TRIANGULAR HULL 1, a DUF640 gene, is associated with
RT grain shape, size and weight in rice.";
RL Sci. China Life Sci. 56:275-283(2013).
RN [11]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=25224972; DOI=10.1266/ggs.89.61;
RA Sato D.S., Ohmori Y., Nagashima H., Toriba T., Hirano H.Y.;
RT "A role for TRIANGULAR HULL1 in fine-tuning spikelet morphogenesis in
RT rice.";
RL Genes Genet. Syst. 89:61-69(2014).
RN [12]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=26486996; DOI=10.1111/jipb.12441;
RA Ren D., Rao Y., Wu L., Xu Q., Li Z., Yu H., Zhang Y., Leng Y., Hu J.,
RA Zhu L., Gao Z., Dong G., Zhang G., Guo L., Zeng D., Qian Q.;
RT "The pleiotropic ABNORMAL FLOWER AND DWARF1 affects plant height, floral
RT development and grain yield in rice.";
RL J. Integr. Plant Biol. 58:529-539(2016).
RN [13]
RP FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, DISRUPTION PHENOTYPE, AND
RP MUTAGENESIS OF ARG-80; GLY-124 AND HIS-129.
RX PubMed=29057928; DOI=10.1038/s41598-017-14146-w;
RA Peng P., Liu L., Fang J., Zhao J., Yuan S., Li X.;
RT "The rice TRIANGULAR HULL1 protein acts as a transcriptional repressor in
RT regulating lateral development of spikelet.";
RL Sci. Rep. 7:13712-13712(2017).
RN [14]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=30725309; DOI=10.1186/s12284-019-0265-2;
RA Wang J., Zhang Q., Wang Y., Huang J., Luo N., Wei S., Jin J.;
RT "Analysing the rice young panicle transcriptome reveals the gene regulatory
RT network controlled by TRIANGULAR HULL1.";
RL Rice 12:6-6(2019).
CC -!- FUNCTION: Transcription factor required for lateral development of the
CC lemma and palea (PubMed:22203474, Ref.9, PubMed:23526395,
CC PubMed:25224972, PubMed:26486996, PubMed:29057928, PubMed:30725309).
CC Involved in the regulation of grain hull development (PubMed:23526395).
CC Possesses transactivation activity in yeast, and may determine grain
CC shape and size by modifying gene expression in the grain hull
CC (PubMed:23526395). Regulates the expression of cell proliferation and
CC expansion related genes (PubMed:26486996). Acts as transcriptional
CC repressor and regulates cell expansion during the lateral development
CC of spikelet (PubMed:29057928). May act upstream of hormone-related
CC genes and starch and sucrose metabolism-related genes, which may be
CC responsible for lemma and palea development, and grain filling,
CC respectively (PubMed:30725309). Does not seem to function at stages of
CC floral-organ initiation and patterning (Ref.9).
CC {ECO:0000269|PubMed:22203474, ECO:0000269|PubMed:23526395,
CC ECO:0000269|PubMed:25224972, ECO:0000269|PubMed:26486996,
CC ECO:0000269|PubMed:29057928, ECO:0000269|PubMed:30725309,
CC ECO:0000269|Ref.9}.
CC -!- SUBUNIT: Homodimer. {ECO:0000269|PubMed:29057928}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:22203474,
CC ECO:0000269|PubMed:23526395, ECO:0000269|PubMed:26486996,
CC ECO:0000269|PubMed:29057928, ECO:0000269|Ref.9}.
CC -!- TISSUE SPECIFICITY: Expressed in lemma, palea, rachis branches, flag
CC leaves and young embryos (PubMed:22203474). Highly expressed in lemmas
CC and paleas of young spikelets (Ref.9, PubMed:23526395,
CC PubMed:26486996). Expressed in stamens, pistil and leaf sheaths
CC (Ref.9). {ECO:0000269|PubMed:22203474, ECO:0000269|PubMed:23526395,
CC ECO:0000269|PubMed:26486996, ECO:0000269|Ref.9}.
CC -!- DISRUPTION PHENOTYPE: Triangular hull with tortuous lemma and palea
CC (PubMed:22203474, PubMed:29057928). Defects in development of lemma and
CC palea, which have a beak-like form (Ref.9, PubMed:25224972,
CC PubMed:30725309). Beak-shaped grains of decreased width, thickness and
CC weight with a loosely interlocked lemma and palea that are unable to
CC close tightly (PubMed:23526395, PubMed:26486996, PubMed:29057928). Poor
CC grain filling (PubMed:22203474, Ref.9, PubMed:23526395,
CC PubMed:25224972, PubMed:26486996, PubMed:29057928, PubMed:30725309).
CC {ECO:0000269|PubMed:22203474, ECO:0000269|PubMed:23526395,
CC ECO:0000269|PubMed:25224972, ECO:0000269|PubMed:26486996,
CC ECO:0000269|PubMed:29057928, ECO:0000269|PubMed:30725309,
CC ECO:0000269|Ref.9}.
CC -!- SIMILARITY: Belongs to the plant homeotic and developmental regulators
CC ALOG protein family. {ECO:0000305}.
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DR EMBL; AB512495; BAI52984.1; -; mRNA.
DR EMBL; AP004081; BAD21590.1; -; Genomic_DNA.
DR EMBL; AP005303; BAD22027.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF10387.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS81516.1; -; Genomic_DNA.
DR EMBL; CM000139; EAZ25035.1; -; Genomic_DNA.
DR EMBL; AK111446; BAG99260.1; -; mRNA.
DR RefSeq; XP_015624971.1; XM_015769485.1.
DR AlphaFoldDB; Q6K5X1; -.
DR STRING; 4530.OS02T0811000-01; -.
DR PaxDb; Q6K5X1; -.
DR PRIDE; Q6K5X1; -.
DR EnsemblPlants; Os02t0811000-01; Os02t0811000-01; Os02g0811000.
DR GeneID; 4331099; -.
DR Gramene; Os02t0811000-01; Os02t0811000-01; Os02g0811000.
DR KEGG; osa:4331099; -.
DR eggNOG; ENOG502QT0B; Eukaryota.
DR HOGENOM; CLU_071168_3_0_1; -.
DR InParanoid; Q6K5X1; -.
DR OMA; ASPQFIM; -.
DR OrthoDB; 1383354at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q6K5X1; OS.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR GO; GO:0009299; P:mRNA transcription; ISS:UniProtKB.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:UniProtKB.
DR GO; GO:0090698; P:post-embryonic plant morphogenesis; ISS:UniProtKB.
DR GO; GO:0080050; P:regulation of seed development; IMP:UniProtKB.
DR GO; GO:0009416; P:response to light stimulus; IBA:GO_Central.
DR InterPro; IPR040222; ALOG.
DR InterPro; IPR006936; ALOG_dom.
DR PANTHER; PTHR31165; PTHR31165; 1.
DR Pfam; PF04852; DUF640; 1.
DR PROSITE; PS51697; ALOG; 1.
PE 1: Evidence at protein level;
KW Developmental protein; DNA-binding; Nucleus; Reference proteome; Repressor;
KW Transcription; Transcription regulation.
FT CHAIN 1..248
FT /note="Protein G1-like6"
FT /id="PRO_0000425308"
FT DOMAIN 80..207
FT /note="ALOG"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01033"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 205..210
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT COMPBIAS 1..15
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MUTAGEN 80
FT /note="R->W: Loss of homodimerization."
FT /evidence="ECO:0000269|PubMed:29057928"
FT MUTAGEN 124
FT /note="G->Q: Loss of homodimerization."
FT /evidence="ECO:0000269|PubMed:29057928"
FT MUTAGEN 129
FT /note="H->Y: Triangular hull 1 phenotype; loss of
FT homodimerization."
FT /evidence="ECO:0000269|PubMed:29057928"
SQ SEQUENCE 248 AA; 25886 MW; A31CC55FC87E3577 CRC64;
MDRHHHHHHH HHHHMMSGGG QDPAAGDGGA GGATQDSFFL GPAAAAMFSG AGSSSSGAGT
SAGGGGGGPS PSSSSPSLSR YESQKRRDWN TFGQYLRNHR PPLSLSRCSG AHVLEFLKYM
DQFGKTKVHT PVCPFYGHPN PPAPCPCPLR QAWGSLDALI GRLRAAYEEN GGTPEMNPFG
ARAVRLYLRE VRETQARARG ISYEKKKRKK PSSAGAGAGP SSEGSPPPPG GSASGGGDTS
ASPQFIIP
