ID   G2_VAR67                Reviewed;         220 AA.
AC   P0DOP7; P32992;
DT   16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2019, sequence version 1.
DT   12-AUG-2020, entry version 5.
DE   RecName: Full=Late transcription elongation factor G2;
DE   AltName: Full=Protein G2;
GN   ORFNames=G2R;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8109158; DOI=10.1016/0168-1702(93)90093-3;
RA   Shchelkunov S.N., Blinov V.M., Resenchuk S.M., Totmenin A.V.,
RA   Sandakhchiev L.S.;
RT   "Analysis of the nucleotide sequence of a 43 kbp segment of the genome of
RT   variola virus India-1967 strain.";
RL   Virus Res. 30:239-258(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8383392; DOI=10.1016/0168-1702(93)90110-9;
RA   Shchelkunov S.N., Blinov V.M., Totmenin A.V., Marennikova S.S.,
RA   Kolykhalov A.A., Frolov I.V., Chizhikov V.E., Gytorov V.V., Gashikov P.V.,
RA   Belanov E.F., Belavin P.A., Resenchuk S.M., Andzhaparidze O.G.,
RA   Sandakhchiev L.S.;
RT   "Nucleotide sequence analysis of variola virus HindIII M, L, I genome
RT   fragments.";
RL   Virus Res. 27:25-35(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
CC   -!- FUNCTION: Involved in postreplicative transcription elongation on
CC       intermediate and late genes. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with H5 and A18. Might be part of a transcription
CC       complex composed at least of G2, A18, and H5 (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae G2 family. {ECO:0000305}.
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DR   EMBL; X67119; CAA47565.1; -; Genomic_DNA.
DR   EMBL; X69198; CAA49006.1; -; Genomic_DNA.
DR   PIR; S33080; S33080.
DR   RefSeq; NP_042109.1; NC_001611.1.
DR   GeneID; 1486431; -.
DR   KEGG; vg:1486431; -.
DR   Proteomes; UP000002060; Genome.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR   InterPro; IPR008446; Chordopox_G2.
DR   Pfam; PF05796; Chordopox_G2; 1.
PE   3: Inferred from homology;
KW   Elongation factor; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..220
FT                   /note="Late transcription elongation factor G2"
FT                   /id="PRO_0000099526"
SQ   SEQUENCE   220 AA;  25741 MW;  B5F6E456C4CDC0C8 CRC64;
     MPFRDLILFN LSKFLLTEDK ESLEIVSSLC RGFEISYDDL ITYFPDRKYH KYIYKVFEHV
     DLSEELSMEF HDTTLRDLVY LKLYKYSKCI RPCYKLGDNL KGIVVIKDRN IYIREANDDL
     IEYLLKEYTP QIYTYSNEHV PIAGSKLILC GFSQVTFMAY TTSHITTNKK VDVLVSKKCI
     DKLVDPINYQ ILQNLFDKGS GTINKILRKI FYSVTGGQTP