G2_VARV
ID G2_VARV Reviewed; 220 AA.
AC P0DOP8; P32992;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 16-OCT-2019, sequence version 1.
DT 29-SEP-2021, entry version 10.
DE RecName: Full=Late transcription elongation factor G2;
DE AltName: Full=Protein G2;
GN ORFNames=G2R;
OS Variola virus.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX NCBI_TaxID=10255;
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Bangladesh-1975;
RX PubMed=8264798; DOI=10.1038/366748a0;
RA Massung R.F., Esposito J.J., Liu L.I., Qi J., Utterback T.R., Knight J.C.,
RA Aubin L., Yuran T.E., Parsons J.M., Loparev V.N., Selivanov N.A.,
RA Cavallaro K.F., Kerlavage A.R., Mahy B.W.J., Venter J.C.;
RT "Potential virulence determinants in terminal regions of variola smallpox
RT virus genome.";
RL Nature 366:748-751(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Garcia-1966;
RA Shchelkunov S.N., Sosnovtsev S.V., Totmenin A.V., Resenchuk S.M.,
RA Blinov V.M., Sandakhchiev L.S.;
RL Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in postreplicative transcription elongation on
CC intermediate and late genes. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with H5 and A18. Might be part of a transcription
CC complex composed at least of G2, A18, and H5 (By similarity).
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the chordopoxvirinae G2 family. {ECO:0000305}.
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DR EMBL; L22579; AAA60813.1; -; Genomic_DNA.
DR EMBL; X76267; CAA53869.1; -; Genomic_DNA.
DR PIR; G72158; G72158.
DR PIR; T28503; T28503.
DR RefSeq; NP_042109.1; NC_001611.1.
DR GeneID; 1486431; -.
DR KEGG; vg:1486431; -.
DR Proteomes; UP000119805; Genome.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR008446; Chordopox_G2.
DR Pfam; PF05796; Chordopox_G2; 1.
PE 3: Inferred from homology;
KW Elongation factor; Protein biosynthesis.
FT CHAIN 1..220
FT /note="Late transcription elongation factor G2"
FT /id="PRO_0000448191"
SQ SEQUENCE 220 AA; 25741 MW; B5F6E456C4CDC0C8 CRC64;
MPFRDLILFN LSKFLLTEDK ESLEIVSSLC RGFEISYDDL ITYFPDRKYH KYIYKVFEHV
DLSEELSMEF HDTTLRDLVY LKLYKYSKCI RPCYKLGDNL KGIVVIKDRN IYIREANDDL
IEYLLKEYTP QIYTYSNEHV PIAGSKLILC GFSQVTFMAY TTSHITTNKK VDVLVSKKCI
DKLVDPINYQ ILQNLFDKGS GTINKILRKI FYSVTGGQTP