ID   G3_FOWPN                Reviewed;         103 AA.
AC   Q9J5D2;
DT   29-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Protein G3 homolog;
DE   AltName: Full=Protein FPV078;
GN   OrderedLocusNames=FPV078;
OS   Fowlpox virus (strain NVSL) (FPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Avipoxvirus.
OX   NCBI_TaxID=928301;
OH   NCBI_TaxID=7742; Vertebrata.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10729156; DOI=10.1128/jvi.74.8.3815-3831.2000;
RA   Afonso C.L., Tulman E.R., Lu Z., Zsak L., Kutish G.F., Rock D.L.;
RT   "The genome of fowlpox virus.";
RL   J. Virol. 74:3815-3831(2000).
CC   -!- FUNCTION: Part of the entry-fusion complex responsible for the virus
CC       membrane fusion with host cell membrane during virus entry. Also plays
CC       a role in cell-cell fusion (syncytium formation) (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Part of a stable entry-fusion complex (EFC) which is at least
CC       composed of proteins A16, A21, A28, G3, G9, H2, J5, and L5. Formation
CC       of the viral membrane is necessary for the assembly of the complex.
CC       Interacts with L5 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion membrane {ECO:0000305}; Single-pass
CC       membrane protein {ECO:0000305}. Note=Component of the mature virion
CC       (MV) membrane. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae G3 family. {ECO:0000305}.
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DR   EMBL; AF198100; AAF44422.1; -; Genomic_DNA.
DR   RefSeq; NP_039042.1; NC_002188.1.
DR   GeneID; 1486626; -.
DR   KEGG; vg:1486626; -.
DR   Proteomes; UP000008597; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0019064; P:fusion of virus membrane with host plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   InterPro; IPR010367; Poxvirus_G3.
DR   Pfam; PF06129; Chordopox_G3; 1.
PE   3: Inferred from homology;
KW   Fusion of virus membrane with host cell membrane;
KW   Fusion of virus membrane with host membrane; Membrane; Reference proteome;
KW   Signal-anchor; Transmembrane; Transmembrane helix;
KW   Viral penetration into host cytoplasm; Virion; Virus entry into host cell.
FT   CHAIN           1..103
FT                   /note="Protein G3 homolog"
FT                   /id="PRO_0000099530"
FT   TRANSMEM        1..21
FT                   /note="Helical; Signal-anchor"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        22..103
FT                   /note="Virion surface"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   103 AA;  12236 MW;  BCE3BF93F3E79914 CRC64;
     MTLFLVIFFI LFLLLCYFFS FKRTNKMEIG INPIKKIPWS DNEHIFVSSL FTNKDKYLTG
     PMRLTYRPDS KTAVLDFKGT NYTYYLDNFD DVRKLVPTLL LSK