ID   G7_VACCC                Reviewed;         371 AA.
AC   P21028;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   29-SEP-2021, entry version 58.
DE   RecName: Full=Assembly protein G7;
GN   ORFNames=G7L;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- FUNCTION: Late protein which is a part of a large complex required for
CC       early virion morphogenesis. This complex participates in the formation
CC       of virosomes and the incorporation of virosomal contents into nascent
CC       immature virions (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Part of a complex composed of A30, G7, F10 kinase, A15, D2,
CC       D3, and J1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250}. Virion
CC       {ECO:0000250}. Note=Localizes in cytoplasmic virus factories and
CC       present in the virion core. {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- PTM: Phosphorylated on serines by F10 kinase, phosphorylation state is
CC       regulated by H1 phosphatase. {ECO:0000250}.
CC   -!- PTM: Undergoes proteolytic processing during morphogenesis, probably
CC       required for the transformation of immature virions (IV) into mature
CC       virions (MV). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae G7 family. {ECO:0000305}.
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DR   EMBL; M35027; AAA48071.1; -; Genomic_DNA.
DR   PIR; C42512; C42512.
DR   Proteomes; UP000008269; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008787; Poxvirus_G7.
DR   Pfam; PF05503; Pox_G7; 1.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Phosphoprotein; Reference proteome; Virion.
FT   CHAIN           1..371
FT                   /note="Assembly protein G7"
FT                   /id="PRO_0000099537"
FT   SITE            187..188
FT                   /note="Cleavage; by I7 protease"
FT                   /evidence="ECO:0000250"
FT   SITE            238..239
FT                   /note="Cleavage; by I7 protease"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   371 AA;  41921 MW;  6FCC21179B659461 CRC64;
     MAAEQRRSTI FDIVSKCIVQ SVLRDISINS EYIESKAKQL CYCPASKKES VINGIYNCCE
     SNIEIMDKEQ LLKILDNLRC HSAHVCNATD FWRLYNSLKR FTHTTAFFNT CKPTILATLN
     TLITLILSNK LLYAAEMVEY LENQLDSSNK SMSQELAELL EMKYALINLV QYRILPMIIG
     EPIIVAGFSG KEPISDYSAE VERLMELPVK TDIVNTTYDF LARKGIDTSN NIAEYIAGLK
     IEEIEKVEKY LPEVISTIAN SNIIKNKKSI FPANINDKQI MECSRMLDTS EKYSKGYKTD
     GAVTSPLTGN NTITTFIPIS ASDMQKFTIL EYLYIMRVMA NNVKKKNVGK NNGGVVMHIN
     SPFKVINLPK C