ID   GAAS1_HUMAN             Reviewed;         125 AA.
AC   O95177; O95176; Q52LX9;
DT   24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Uncharacterized protein GAS8-AS1 {ECO:0000312|HGNC:HGNC:1197};
DE   AltName: Full=GAS8 antisense RNA 1 {ECO:0000312|HGNC:HGNC:1197};
DE   AltName: Full=GAS8 antisense gene protein 1 {ECO:0000305};
GN   Name=GAS8-AS1 {ECO:0000312|HGNC:HGNC:1197};
GN   Synonyms=C16orf3 {ECO:0000312|HGNC:HGNC:1197};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND VARIANT 47-PRO--CYS-54 DEL.
RX   PubMed=9790751; DOI=10.1006/geno.1998.5457;
RA   Whitmore S.A., Settasatian C., Crawford J., Lower K.M., McCallum B.,
RA   Seshadri R., Cornelisse C.J., Moerland E.W., Cleton-Jansen A.-M.,
RA   Tipping A.J., Mathew C.G., Savnio M., Savoia A., Verlander P.,
RA   Auerbach A.D., Van Berkel C., Pronk J.C., Doggett N.A., Callen D.F.;
RT   "Characterization and screening for mutations of the growth arrest-specific
RT   11 (GAS11) and C16orf3 genes at 16q24.3 in breast cancer.";
RL   Genomics 52:325-331(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA   Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA   Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA   Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA   Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA   Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA   Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA   Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA   Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA   Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA   Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA   Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA   Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA   Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA   Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA   Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA   Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA   DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA   Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA   Myers R.M., Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT 47-PRO--CYS-54 DEL.
RC   TISSUE=Brain, and Brain cortex;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- POLYMORPHISM: There seem to be two alleles of this protein.
CC   -!- CAUTION: Product of a dubious CDS prediction. May be a non-coding RNA.
CC       No experimental confirmation available. {ECO:0000305}.
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DR   EMBL; AF050080; AAC69520.1; -; mRNA.
DR   EMBL; AF050081; AAC69521.1; -; mRNA.
DR   EMBL; AC133919; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC093751; AAH93751.1; -; mRNA.
DR   EMBL; BC104849; AAI04850.1; -; mRNA.
DR   AlphaFoldDB; O95177; -.
DR   SMR; O95177; -.
DR   BioMuta; HGNC:1197; -.
DR   PRIDE; O95177; -.
DR   ProteomicsDB; 50688; -.
DR   GeneCards; GAS8-AS1; -.
DR   HGNC; HGNC:1197; GAS8-AS1.
DR   MalaCards; GAS8-AS1; -.
DR   MIM; 605179; gene.
DR   neXtProt; NX_O95177; -.
DR   Orphanet; 146; Differentiated thyroid carcinoma.
DR   InParanoid; O95177; -.
DR   PathwayCommons; O95177; -.
DR   Pharos; O95177; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; O95177; protein.
PE   5: Uncertain;
KW   Reference proteome; Repeat.
FT   CHAIN           1..125
FT                   /note="Uncharacterized protein GAS8-AS1"
FT                   /id="PRO_0000079278"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          81..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..125
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         47..54
FT                   /note="Missing (in short isoform)"
FT                   /evidence="ECO:0000269|PubMed:15489334,
FT                   ECO:0000269|PubMed:9790751"
FT                   /id="VAR_010243"
FT   VARIANT         72
FT                   /note="V -> I (in dbSNP:rs3785183)"
FT                   /id="VAR_056843"
SQ   SEQUENCE   125 AA;  12619 MW;  ACCA40DBEE0A79B4 CRC64;
     MKLSSAAGQE SPGHPHPSPP AWTLKKPSES VAQRAMCSAR ACPVACPVGC PAACPVGCPI
     ACPVSCPVAC PVGCPVGSMA TAPQGLSPQE WEADRETGSS SHAGTTQCSI HSPSSSSRHL
     SRTQT