ID   GAGJ_DROFU              Reviewed;         574 AA.
AC   P21331;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Nucleic-acid-binding protein from mobile element jockey;
DE   AltName: Full=ORF1;
GN   Name=gag;
OS   Drosophila funebris (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1911.1;
RX   PubMed=1701254; DOI=10.1073/pnas.87.23.9216;
RA   Mizrokhi L.J., Mazo A.M.;
RT   "Evidence for horizontal transmission of the mobile element jockey between
RT   distant Drosophila species.";
RL   Proc. Natl. Acad. Sci. U.S.A. 87:9216-9220(1990).
CC   -!- FUNCTION: Strongly basic protein that binds directly to retroviral RNA
CC       and may be involved in its packaging and in the reverse transcription
CC       process.
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DR   EMBL; M38437; AAA28648.1; -; Genomic_DNA.
DR   AlphaFoldDB; P21331; -.
DR   SMR; P21331; -.
DR   FlyBase; FBgn0019259; Dfun\jockey\gag.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR006579; Pre_C2HC_dom.
DR   Pfam; PF07530; PRE_C2HC; 1.
DR   SMART; SM00596; PRE_C2HC; 1.
PE   4: Predicted;
KW   Metal-binding; Transposable element; Zinc; Zinc-finger.
FT   CHAIN           1..574
FT                   /note="Nucleic-acid-binding protein from mobile element
FT                   jockey"
FT                   /id="PRO_0000087421"
FT   ZN_FING         393..406
FT                   /evidence="ECO:0000255"
FT   ZN_FING         412..426
FT                   /evidence="ECO:0000255"
FT   ZN_FING         433..447
FT                   /evidence="ECO:0000255"
FT   REGION          393..447
FT                   /note="Three zinc-finger-like regions"
SQ   SEQUENCE   574 AA;  62663 MW;  2ADAE72F8A3BF1B7 CRC64;
     MNYGNSSTRS LPSDRSAKLE EMRKIAGADP ATIRSQIIAS GASTSNQAAS LLANSAFNYP
     SVTTSSDTSF TCTVTTSQAS CASTSTYTVA ARVGPNICST TPVGNNSVSD TMAQMAGKAA
     RKGKCSFQAP GLSSSKKRKV VVNACQTIRK VKMQATDLRK ATPKVATASA TATTMSNNRF
     AALALEADNV MEQDLAENCS NGEEDVPVVN MNRQSTNGPS KPPAICVPNV DNPHSLEQAL
     NSCVGDNSYS IRTSKFGVSR IYTINADAFR AVVKHLTSLN CQFWHHQLRE DKPYTVAVKG
     MHANVPKAQI EHAFADHGFE ALNIYCPRKA DWRNAQVSED DDEATVNFKT RQNMFFVNLK
     QGPKIAEALK ITQLGRYRVT VERAPRRREV LQCLRCHIFG HSKNYCVRDP ICAKCAGSHM
     TGSLLCTSDI CMCVNCGGDH ASTDKDCPVR IEKLRKMKPS PRLPVPDNAT NNKHNRASSA
     RGFIPAEAVR GNMSYADIVR PKGSQFRATA TINSQHESNP LHDLGSGNKF LTLEKSIREI
     NGRMDQLFKL VQETVEANKA FRELVQVLIS RMPK