ID   GAGJ_DROME              Reviewed;         568 AA.
AC   P21330;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Nucleic-acid-binding protein from mobile element jockey;
DE   AltName: Full=ORF1;
GN   Name=gag;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2463954; DOI=10.1016/0378-1119(88)90197-7;
RA   Priimaegi A.F., Mizrokhi L.J., Ilyin Y.V.;
RT   "The Drosophila mobile element jockey belongs to LINEs and contains coding
RT   sequences homologous to some retroviral proteins.";
RL   Gene 70:253-262(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3040362;
RA   Mizrokhi L.J., Priimaegi A.F., Ilyin Y.V.;
RT   "Drosophila mobile element jockey is a retroposon and encodes the GAG-
RT   specific protein sequence characteristic for retroviruses.";
RL   Dokl. Akad. Nauk SSSR 294:1235-1239(1987).
CC   -!- FUNCTION: Strongly basic protein that binds directly to retroviral RNA
CC       and may be involved in its packaging and in the reverse transcription
CC       process.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA28674.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAA28939.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M22874; AAA28674.1; ALT_INIT; Genomic_DNA.
DR   EMBL; M38643; AAA28939.1; ALT_INIT; Genomic_DNA.
DR   PIR; JT0395; JT0395.
DR   AlphaFoldDB; P21330; -.
DR   SMR; P21330; -.
DR   PRIDE; P21330; -.
DR   FlyBase; FBgn0020297; jockey\gag.
DR   PRO; PR:P21330; -.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR006579; Pre_C2HC_dom.
DR   Pfam; PF07530; PRE_C2HC; 1.
DR   SMART; SM00596; PRE_C2HC; 1.
PE   4: Predicted;
KW   Metal-binding; Transposable element; Zinc; Zinc-finger.
FT   CHAIN           1..568
FT                   /note="Nucleic-acid-binding protein from mobile element
FT                   jockey"
FT                   /id="PRO_0000087422"
FT   ZN_FING         390..403
FT                   /evidence="ECO:0000255"
FT   ZN_FING         403..423
FT                   /evidence="ECO:0000255"
FT   ZN_FING         430..444
FT                   /evidence="ECO:0000255"
FT   REGION          128..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          189..218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          390..444
FT                   /note="Three zinc-finger-like regions"
FT   COMPBIAS        151..170
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   568 AA;  62878 MW;  DE0E4834A24C759A CRC64;
     MENSFAQSRP SNGCDKFEKM RKVAGVEPGE LRSQLRASCA VVSPNLEGMP TQSAVSSLMV
     TISSNTNASV TCTISNVQAN MICTPTYTDC TTVTTSICPT TPYDNGLPTP LSSLPNKPSK
     ANCPFQAHDR TVNRKRKGVS QPPLPILTPS PSRKTKRQAT MPLNEEASTS TAAALNNNRF
     ALLSAEAENM EQDVSDADSD IEDSAARDGG GQSAKYSKPP AICVPSVSDP VTLERALNLS
     TGSSNYYIRI SRFGVSRIYT ANPDAFRTAV KELNKLNCQF WHHQLKEEKP YRVVLKGIHA
     NVPSSQIEQA FSDHGYEVLN IYCPRKSDWK NIQVNEDDNE ATKNFKTRQN LFYINLKQGP
     NVKESLKITR LGRYRVTVER ATRRKELLQC QRCQIFGHSK NYCAQDPICG KCSGPHMTGF
     ALCISDVCLC INCGGDHVST DKSCPVRAEK AKKLKPRSRL PMTNNIATLK PPQRSSSGYI
     PAEALRTNIS YADIARRNTT QSRARATVQA EVIPTSDNSL NNKFMTLDNS IRAINTRMDE
     LFKLIHETVE ANKAFRELVQ VLITRIPK