ID   GAGXE_DROME             Reviewed;         501 AA.
AC   Q9NBX5;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Nucleic-acid-binding protein from transposon X-element;
GN   Name=ORF1 {ECO:0000312|FlyBase:FBgn0041613};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1] {ECO:0000312|EMBL:AAF81410.1}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11405632; DOI=10.1007/s004380000437;
RA   Tudor M., Davis A.J., Feldman M., Grammatikaki M., O'Hare K.;
RT   "The X element, a novel LINE transposable element from Drosophila
RT   melanogaster.";
RL   Mol. Genet. Genomics 265:489-496(2001).
CC   -!- FUNCTION: Strongly basic protein that binds directly to retroviral RNA
CC       and may be involved in its packaging and in the reverse transcription
CC       process. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
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DR   EMBL; AF237761; AAF81410.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9NBX5; -.
DR   SMR; Q9NBX5; -.
DR   FlyBase; FBgn0041613; X-element\ORF1.
DR   PRO; PR:Q9NBX5; -.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IMP:UniProtKB.
DR   InterPro; IPR006579; Pre_C2HC_dom.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   Pfam; PF07530; PRE_C2HC; 1.
DR   SMART; SM00596; PRE_C2HC; 1.
DR   SUPFAM; SSF57756; SSF57756; 1.
PE   4: Predicted;
KW   Metal-binding; Transposable element; Virion; Zinc; Zinc-finger.
FT   CHAIN           1..501
FT                   /note="Nucleic-acid-binding protein from transposon X-
FT                   element"
FT                   /id="PRO_0000076222"
FT   ZN_FING         285..302
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000255"
FT   REGION          20..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          105..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          353..385
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          400..443
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        35..52
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        53..67
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        400..422
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   501 AA;  55743 MW;  8CF7DC607D037910 CRC64;
     MNTLNETAAA DESLDTAFLS SPQCAAPQRF QKIKRKSRAS PETERKKPKS TIGKQGENPS
     ATEPRYGGNS NRFGLLAHLT ADKQVGNEIG DLYDQPSTSH QAAIAAAKRD AASAGTTSSA
     KRAQSKPPPI VMEGVDDVYL MMQSIENIVD LEKIEARASM SGVLRLYAAD ANTFRTIVNW
     LEIEEYEFHC YQLKEDRPYR VCVKGLHHST LHHQIKDELE KIGHKVLDIH TPLRRNEPGT
     SKASPVNMFF LNIAAAANNK EILAVKALCH MRVVIEPLRK RNAIVQCHRC QQIGHTAKYC
     RKAHICVKCA GEHPAKDCTR PRIELCTCYN CGGQHPANYK GCSKLQAFLQ RSRPRSGVAG
     RTEVSDRPTP RGLAGGKEIP SSRGGISYAD VARGSIHHKQ PMSLTHQQQK QKQQPYDGSP
     SRQRSRSRTR ASRGTLQRST DASSSIEAIL QTLNENINSL RSIQEKQMEL MMMMMKQQQQ
     QSHQQGQIIN LLTALQARQA P