ID   GAG_AVEV1               Reviewed;         239 AA.
AC   P06936; Q64986; Q64987; Q64988;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   29-SEP-2021, entry version 81.
DE   RecName: Full=Gag polyprotein;
DE   AltName: Full=Core polyprotein;
DE   Contains:
DE     RecName: Full=Matrix protein p19;
DE   Contains:
DE     RecName: Full=Core protein p23;
DE   Contains:
DE     RecName: Full=Core protein p2;
DE   Contains:
DE     RecName: Full=Core protein p10;
DE   Flags: Fragment;
GN   Name=ev-1;
OS   Avian endogenous virus EV-1.
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Alpharetrovirus.
OX   NCBI_TaxID=11859;
OH   NCBI_TaxID=8976; Galliformes.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2993659; DOI=10.1128/jvi.56.1.31-39.1985;
RA   Vogt V.M., Pepinsky R.B., Southard L.E.;
RT   "Primary structure of p19 species of avian sarcoma and leukemia viruses.";
RL   J. Virol. 56:31-39(1985).
CC   -!- SUBCELLULAR LOCATION: [Matrix protein p19]: Virion {ECO:0000305}.
CC   -!- DOMAIN: Late-budding domains (L domains) are short sequence motifs
CC       essential for viral particle budding. They recruit proteins of the host
CC       ESCRT machinery (Endosomal Sorting Complex Required for Transport) or
CC       ESCRT-associated proteins. Gag contains one L domain: a PPXY motif
CC       which potentially interacts with the WW domain 3 of NEDD4 E3 ubiquitin
CC       ligase (Potential). {ECO:0000305}.
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DR   EMBL; M30517; AAA42567.1; -; Genomic_RNA.
DR   PIR; A25317; A25317.
DR   SMR; P06936; -.
DR   GO; GO:0039660; F:structural constituent of virion; IEA:UniProtKB-KW.
DR   GO; GO:0039702; P:viral budding via host ESCRT complex; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.150.90; -; 1.
DR   InterPro; IPR004028; Gag_M.
DR   InterPro; IPR012344; Matrix_HIV/RSV_N.
DR   InterPro; IPR010999; Retrovr_matrix.
DR   Pfam; PF02813; Retro_M; 1.
DR   SUPFAM; SSF47836; SSF47836; 1.
PE   4: Predicted;
KW   Host-virus interaction; Viral budding;
KW   Viral budding via the host ESCRT complexes; Viral matrix protein;
KW   Viral release from host cell; Virion.
FT   CHAIN           1..177
FT                   /note="Core protein p23"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000040809"
FT   CHAIN           1..155
FT                   /note="Matrix protein p19"
FT                   /id="PRO_0000040810"
FT   CHAIN           156..177
FT                   /note="Core protein p2"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000040811"
FT   CHAIN           178..239
FT                   /note="Core protein p10"
FT                   /id="PRO_0000040812"
FT   REGION          124..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          184..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           172..175
FT                   /note="PPXY motif"
FT                   /evidence="ECO:0000255"
FT   NON_TER         239
SQ   SEQUENCE   239 AA;  24813 MW;  AC9DAA707AE990D7 CRC64;
     MEAVIKVISS ACKTYCGKTS PSKKEIGAML SLLQKEGLLM SPSDLYSPGS WDPITAALSQ
     RAMVLGKSGE LKTWGLVLGA LKAAREEQVT SEQAKFWLGL GGGRVSPPGP ECIEKPATER
     RIDKGEEVGE TTAQRDAKMA PEKMATPKTV GTSCYQCGTA TGCNCATASA PPPPYVGSGL
     YPSLAGVGEQ QGQGGDTPWG AEQPRAEPGH AGLAPGPALT DWARIREELA STGPPVVAM