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GAG_IPMAE
ID   GAG_IPMAE               Reviewed;         255 AA.
AC   P31790;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   23-FEB-2022, entry version 53.
DE   RecName: Full=Intracisternal A-particle Gag-related polyprotein;
GN   Name=gag;
OS   Mouse intracisternal a-particle MIAE (IAP-MIAE).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Intracisternal A-particles.
OX   NCBI_TaxID=11932;
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1920613; DOI=10.1128/jvi.65.11.5702-5709.1991;
RA   Reuss F.U., Schaller H.C.;
RT   "cDNA sequence and genomic characterization of intracisternal A-particle-
RT   related retroviral elements containing an envelope gene.";
RL   J. Virol. 65:5702-5709(1991).
CC   -!- MISCELLANEOUS: Intracisternal A-particle Gag-related polyprotein:
CC       Intracisternal A particles (IAPs) are defective retroviral elements.
CC       Due to extensive mutations in the envelope coding sequence, IAPs can
CC       only form defective viral particles confined to the intracisternae of
CC       the Golgi. IAPs are an important class of transposable elements that
CC       induce genomic mutations and cell transformation by disrupting gene
CC       expression. {ECO:0000305}.
CC   -!- MISCELLANEOUS: Readthrough of the terminator UAA occurs between the
CC       codons for Met-218 and Ala-219.
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DR   EMBL; M73818; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; B41305; FOMSIE.
DR   PRIDE; P31790; -.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 1.10.150.490; -; 1.
DR   InterPro; IPR003322; B_retro_matrix.
DR   InterPro; IPR038124; B_retro_matrix_sf.
DR   InterPro; IPR010999; Retrovr_matrix.
DR   Pfam; PF02337; Gag_p10; 1.
DR   SUPFAM; SSF47836; SSF47836; 1.
PE   2: Evidence at transcript level;
KW   Transposable element.
FT   CHAIN           1..255
FT                   /note="Intracisternal A-particle Gag-related polyprotein"
FT                   /id="PRO_0000125479"
FT   REGION          135..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        135..174
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        200..230
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   255 AA;  28610 MW;  5CD99373200D0E8D CRC64;
     MGISHSIVVA LRSVLKQCGL KIATKTLEGF VREIDRVAPW YACSGSLTVA SWDKLKGDLV
     REQQKGKLKA GIIPLWKLVK SCLTDEDCQQ MVEAGQKVLD EIQESLSEVE RGEKVKVERK
     QSALKNLGLS TGLEPEEKRY KGKNALGEIR KRDEKGEKKG DRAGEAHKER SLYPPLVEFK
     QLTLSNSEPD EGVSTSEETD SEEEAVRYKG ERYQQDKMAT QPRKRQKAAD ESQLAAWPPD
     CRLQGPSAPP LYVQR
 
 
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