GAG_IPMAE
ID GAG_IPMAE Reviewed; 255 AA.
AC P31790;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1993, sequence version 1.
DT 23-FEB-2022, entry version 53.
DE RecName: Full=Intracisternal A-particle Gag-related polyprotein;
GN Name=gag;
OS Mouse intracisternal a-particle MIAE (IAP-MIAE).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Retroviridae; Intracisternal A-particles.
OX NCBI_TaxID=11932;
OH NCBI_TaxID=10090; Mus musculus (Mouse).
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1920613; DOI=10.1128/jvi.65.11.5702-5709.1991;
RA Reuss F.U., Schaller H.C.;
RT "cDNA sequence and genomic characterization of intracisternal A-particle-
RT related retroviral elements containing an envelope gene.";
RL J. Virol. 65:5702-5709(1991).
CC -!- MISCELLANEOUS: Intracisternal A-particle Gag-related polyprotein:
CC Intracisternal A particles (IAPs) are defective retroviral elements.
CC Due to extensive mutations in the envelope coding sequence, IAPs can
CC only form defective viral particles confined to the intracisternae of
CC the Golgi. IAPs are an important class of transposable elements that
CC induce genomic mutations and cell transformation by disrupting gene
CC expression. {ECO:0000305}.
CC -!- MISCELLANEOUS: Readthrough of the terminator UAA occurs between the
CC codons for Met-218 and Ala-219.
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DR EMBL; M73818; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; B41305; FOMSIE.
DR PRIDE; P31790; -.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.10.150.490; -; 1.
DR InterPro; IPR003322; B_retro_matrix.
DR InterPro; IPR038124; B_retro_matrix_sf.
DR InterPro; IPR010999; Retrovr_matrix.
DR Pfam; PF02337; Gag_p10; 1.
DR SUPFAM; SSF47836; SSF47836; 1.
PE 2: Evidence at transcript level;
KW Transposable element.
FT CHAIN 1..255
FT /note="Intracisternal A-particle Gag-related polyprotein"
FT /id="PRO_0000125479"
FT REGION 135..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..230
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 255 AA; 28610 MW; 5CD99373200D0E8D CRC64;
MGISHSIVVA LRSVLKQCGL KIATKTLEGF VREIDRVAPW YACSGSLTVA SWDKLKGDLV
REQQKGKLKA GIIPLWKLVK SCLTDEDCQQ MVEAGQKVLD EIQESLSEVE RGEKVKVERK
QSALKNLGLS TGLEPEEKRY KGKNALGEIR KRDEKGEKKG DRAGEAHKER SLYPPLVEFK
QLTLSNSEPD EGVSTSEETD SEEEAVRYKG ERYQQDKMAT QPRKRQKAAD ESQLAAWPPD
CRLQGPSAPP LYVQR