ID   GAG_SCVLB               Reviewed;         697 AA.
AC   Q87026;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   02-JUN-2021, entry version 49.
DE   RecName: Full=Major capsid protein;
DE   AltName: Full=Gag protein;
DE   AltName: Full=Major coat protein;
GN   Name=gag;
OS   Saccharomyces cerevisiae virus L-BC (ScV-L-BC) (ScVLa).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Chrymotiviricetes;
OC   Ghabrivirales; Totiviridae; Totivirus.
OX   NCBI_TaxID=42478;
OH   NCBI_TaxID=4932; Saccharomyces cerevisiae (Baker's yeast).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8607277; DOI=10.1006/viro.1996.0083;
RA   Park C.M., Lopinski J.D., Masuda J., Tzeng T.H., Bruenn J.A.;
RT   "A second double-stranded RNA virus from yeast.";
RL   Virology 216:451-454(1996).
CC   -!- FUNCTION: Capsid protein self-assembles to form an icosahedral capsid
CC       with a T=2 symmetry, about 40 nm in diameter, and consisting of 60
CC       capsid proteins asymmetric dimers. The capsid encapsulates the genomic
CC       dsRNA and the polymerase and remains intact following cell entry to
CC       protect the dsRNA from degradation and to prevent unfavorable antiviral
CC       responses in the host cell during all the replication cycle of the
CC       virus. Nascent transcripts are transcribed within the structural
CC       confines of the virion and are extruded into the cytoplasm (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC       Name=Major capsid protein; Synonyms=Gag protein;
CC         IsoId=Q87026-1; Sequence=Displayed;
CC       Name=RNA-directed RNA polymerase; Synonyms=Pol protein;
CC         IsoId=P23172-1; Sequence=External;
CC   -!- MISCELLANEOUS: [Isoform Major capsid protein]: Produced by conventional
CC       translation.
CC   -!- SIMILARITY: Belongs to the totivirus major capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; U01060; AAB02145.1; -; Genomic_RNA.
DR   RefSeq; NP_042580.1; NC_001641.1. [Q87026-1]
DR   GeneID; 1403711; -.
DR   KEGG; vg:1403711; -.
DR   Proteomes; UP000207604; Genome.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1840.10; -; 1.
DR   InterPro; IPR015302; Major_coat_LA-virus.
DR   InterPro; IPR036332; Major_coat_LA-virus_sf.
DR   Pfam; PF09220; LA-virus_coat; 1.
DR   SUPFAM; SSF82856; SSF82856; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Reference proteome; Ribosomal frameshifting; RNA-binding;
KW   Virion.
FT   CHAIN           1..697
FT                   /note="Major capsid protein"
FT                   /id="PRO_0000402408"
FT   REGION          666..697
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   697 AA;  78316 MW;  0F219E8B0B438E5D CRC64;
     MSSLLNSLLP EYFKPKTNLN INSSRVQYGF NARIDMQYED DSGTRKGSRP NAFMSNTVAF
     IGNYEGIIVD DIPILDGLRA DIFDTHGDLD MGLVEDALSK STMIRRNVPT YTAYASELLY
     KRNLTSLFYN MLRLYYIKKW GSIKYEKDAI FYDNGHACLL NRQLFPKSRD ASLESSLSLP
     EAEIAMLDPG LEFPEEDVPA ILWHGRVSSR ATCILGQACS EFAPLAPFSI AHYSPQLTRK
     LFVNAPAGIE PSSGRYTHED VKDAITILVS ANQAYTDFEA AYLMLAQTLV SPVPRTAEAS
     AWFINAGMVN MPTLSCANGY YPALTNVNPY HRLDTWKDTL NHWVAYPDML FYHSVAMIES
     CYVELGNVAR VSDSDAINKY TFTELSVQGR PVMNRGIIVD LTLVAMRTGR EISLPYPVSC
     GLTRTDALLQ GTEIHVPVVV KDIDMPQYYN AIDKDVIEGQ ETVIKVKQLP PAMYPIYTYG
     INTTEFYSDH FEDQVQVEMA PIDNGKAVFN DARKFSKFMS IMRMMGNDVT ATDLVTGRKV
     SNWADNSSGR FLYTDVKYEG QTAFLVDMDT VKARDHCWVS IVDPNGTMNL SYKMTNFRAA
     MFSRNKPLYM TGGSVRTIAT GNYRDAAERL RAMDETLRLK PFKITEKLDF RVAAYAIPSL
     SGSNMPSLHH QEQLQISEVD AEPINPIGED ELPPDIE