GAK1B_RAT
ID GAK1B_RAT Reviewed; 516 AA.
AC Q6P7B4;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Golgi-associated kinase 1B {ECO:0000305};
DE AltName: Full=Expressed in nerve and epithelium during development;
DE AltName: Full=Protein FAM198B;
GN Name=Gask1b {ECO:0000312|RGD:735075}; Synonyms=Ened, Fam198b;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Prostate;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000250|UniProtKB:Q6UWH4}; Single-pass type II membrane protein
CC {ECO:0000250|UniProtKB:Q6UWH4}.
CC -!- SIMILARITY: Belongs to the GASK family. {ECO:0000305}.
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DR EMBL; BC061747; AAH61747.1; -; mRNA.
DR RefSeq; NP_954536.1; NM_199105.1.
DR RefSeq; XP_006232576.1; XM_006232514.3.
DR AlphaFoldDB; Q6P7B4; -.
DR STRING; 10116.ENSRNOP00000013525; -.
DR GlyGen; Q6P7B4; 1 site.
DR jPOST; Q6P7B4; -.
DR PaxDb; Q6P7B4; -.
DR PRIDE; Q6P7B4; -.
DR Ensembl; ENSRNOT00000013524; ENSRNOP00000013525; ENSRNOG00000010183.
DR GeneID; 310540; -.
DR KEGG; rno:310540; -.
DR UCSC; RGD:735075; rat.
DR CTD; 51313; -.
DR RGD; 735075; Gask1b.
DR eggNOG; ENOG502QU38; Eukaryota.
DR GeneTree; ENSGT00420000029769; -.
DR HOGENOM; CLU_033542_2_0_1; -.
DR InParanoid; Q6P7B4; -.
DR OMA; PPWFSAQ; -.
DR OrthoDB; 451767at2759; -.
DR PhylomeDB; Q6P7B4; -.
DR TreeFam; TF330994; -.
DR PRO; PR:Q6P7B4; -.
DR Proteomes; UP000002494; Chromosome 2.
DR Bgee; ENSRNOG00000010183; Expressed in lung and 19 other tissues.
DR Genevisible; Q6P7B4; RN.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR029207; FAM198.
DR PANTHER; PTHR15905; PTHR15905; 1.
DR Pfam; PF15051; FAM198; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Signal-anchor;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..516
FT /note="Golgi-associated kinase 1B"
FT /id="PRO_0000288904"
FT TOPO_DOM 1..37
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..55
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 56..516
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT CARBOHYD 286
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 516 AA; 58206 MW; CBF1FCD4340CBA6C CRC64;
MTCPDKLGQL INWFVCSLCA PRVCKLWSSR RPRTRRNLLL GTACAIYLGF LVSQVGKGSF
QHGQATNRGP PNNQDIFKVP FPEIPLDGTL APPESQGNGS TLQPNVVYIT LRSKRSKPAN
IRGTVKPKRR KKYAVASVAP DQEVLVRPSL IQPEVARAAD AEVPGYVQGY LTKVGERPWR
MLHGPRVRGS NLQQPRAPES NIRIYSESAP SWLSKEDIRR MRLLADGEVA SILPTIFEGG
TRLLMLEGST SGSVPGCGPS PCGLLKQPLD MSEVFAFHLD RILGLNRTLP SVSRKLEFIQ
DGRPRPIILW DSSLVPSSNV SHSSVKITWG TYQQLLKQKC WLNGRVPRPE WGCTEVHHHE
WSKMALFDFL LQIYNRLDTN CCGFRPRKED ACVQNGLRPN CEDQSSVTLA HIIQRKNDPR
HLVFINNKGF FDRSEDNLNF KLLEGIREFP ESAVSVLKSQ HLRQKLLQSL FLDQVYWESQ
GGRQGIEKLI DVIERRARIL ITYINAHGAR VLPMNE
