GALA_ALLMI
ID GALA_ALLMI Reviewed; 29 AA.
AC P47215;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 16-JAN-2004, sequence version 2.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Galanin;
GN Name=GAL;
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496;
RN [1]
RP PROTEIN SEQUENCE, AND AMIDATION AT ALA-29.
RC TISSUE=Stomach;
RX PubMed=7524049; DOI=10.1016/0196-9781(94)90082-5;
RA Wang Y., Conlon J.M.;
RT "Purification and primary structure of galanin from the alligator
RT stomach.";
RL Peptides 15:603-606(1994).
CC -!- FUNCTION: Contracts smooth muscle of the gastrointestinal and
CC genitourinary tract, regulates growth hormone release, modulates
CC insulin release, and may be involved in the control of adrenal
CC secretion.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the galanin family. {ECO:0000305}.
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DR AlphaFoldDB; P47215; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR008174; Galanin.
DR InterPro; IPR008175; Galanin_pre.
DR PANTHER; PTHR16839; PTHR16839; 1.
DR Pfam; PF01296; Galanin; 1.
DR PRINTS; PR00273; GALANIN.
DR PROSITE; PS00861; GALANIN; 1.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Hormone; Neuropeptide; Secreted.
FT PEPTIDE 1..29
FT /note="Galanin"
FT /id="PRO_0000043874"
FT MOD_RES 29
FT /note="Alanine amide"
FT /evidence="ECO:0000269|PubMed:7524049"
SQ SEQUENCE 29 AA; 3177 MW; F71F019B2D3E0529 CRC64;
GWTLNSAGYL LGPHAIDNHR SFNEKHGIA