ID   GALA_CHICK              Reviewed;          29 AA.
AC   P30802;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Galanin;
GN   Name=GAL; Synonyms=GALN;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT THR-29.
RC   TISSUE=Intestine;
RX   PubMed=1715289; DOI=10.1016/0014-5793(91)81023-2;
RA   Norberg A., Sillard R., Carlquist M., Joernvall H., Mutt V.;
RT   "Chemical detection of natural peptides by specific structures. Isolation
RT   of chicken galanin by monitoring for its N-terminal dipeptide, and
RT   determination of the amino acid sequence.";
RL   FEBS Lett. 288:151-153(1991).
CC   -!- FUNCTION: Contracts smooth muscle of the gastrointestinal and
CC       genitourinary tract, regulates growth hormone release, modulates
CC       insulin release, and may be involved in the control of adrenal
CC       secretion.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the galanin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; S17147; S17147.
DR   AlphaFoldDB; P30802; -.
DR   PaxDb; P30802; -.
DR   HOGENOM; CLU_166244_0_0_1; -.
DR   OrthoDB; 1518030at2759; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR008174; Galanin.
DR   Pfam; PF01296; Galanin; 1.
DR   PRINTS; PR00273; GALANIN.
DR   PROSITE; PS00861; GALANIN; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Neuropeptide;
KW   Reference proteome; Secreted.
FT   PEPTIDE         1..29
FT                   /note="Galanin"
FT                   /id="PRO_0000043873"
FT   MOD_RES         29
FT                   /note="Threonine amide"
FT                   /evidence="ECO:0000269|PubMed:1715289"
SQ   SEQUENCE   29 AA;  3212 MW;  EB66919B2D271629 CRC64;
     GWTLNSAGYL LGPHAVDNHR SFNDKHGFT