GALA_ONCMY
ID GALA_ONCMY Reviewed; 29 AA.
AC P47213;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 25-MAY-2022, entry version 59.
DE RecName: Full=Galanin;
GN Name=gal;
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022;
RN [1]
RP PROTEIN SEQUENCE, AND AMIDATION AT ALA-29.
RC TISSUE=Stomach;
RX PubMed=7532194; DOI=10.1002/cne.903500105;
RA Anglade I., Wang Y., Jensen J., Tramu G., Kah O., Conlon J.M.;
RT "Characterization of trout galanin and its distribution in trout brain and
RT pituitary.";
RL J. Comp. Neurol. 350:63-74(1994).
CC -!- FUNCTION: Contracts smooth muscle of the gastrointestinal and
CC genitourinary tract, regulates growth hormone release, modulates
CC insulin release, and may be involved in the control of adrenal
CC secretion.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the galanin family. {ECO:0000305}.
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DR AlphaFoldDB; P47213; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR008174; Galanin.
DR Pfam; PF01296; Galanin; 1.
DR PRINTS; PR00273; GALANIN.
DR PROSITE; PS00861; GALANIN; 1.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Hormone; Neuropeptide; Secreted.
FT PEPTIDE 1..29
FT /note="Galanin"
FT /id="PRO_0000043876"
FT MOD_RES 29
FT /note="Alanine amide"
FT /evidence="ECO:0000269|PubMed:7532194"
SQ SEQUENCE 29 AA; 3044 MW; 73C37190403FA349 CRC64;
GWTLNSAGYL LGPHGIDGHR TLSDKHGLA