ID   GALA_SHEEP              Reviewed;          29 AA.
AC   P31234;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Galanin;
GN   Name=GAL; Synonyms=GALN, GLNN;
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Ovis.
OX   NCBI_TaxID=9940;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT ALA-29.
RC   TISSUE=Brain;
RX   PubMed=1724081; DOI=10.1016/0196-9781(91)90146-g;
RA   Sillard R., Langel U., Joernvall H.;
RT   "Isolation and characterization of galanin from sheep brain.";
RL   Peptides 12:855-859(1991).
CC   -!- FUNCTION: Contracts smooth muscle of the gastrointestinal and
CC       genitourinary tract, regulates growth hormone release, modulates
CC       insulin release, and may be involved in the control of adrenal
CC       secretion.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the galanin family. {ECO:0000305}.
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DR   AlphaFoldDB; P31234; -.
DR   STRING; 9940.ENSOARP00000017178; -.
DR   eggNOG; ENOG502RZ1E; Eukaryota.
DR   Proteomes; UP000002356; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR008174; Galanin.
DR   InterPro; IPR008175; Galanin_pre.
DR   PANTHER; PTHR16839; PTHR16839; 1.
DR   Pfam; PF01296; Galanin; 1.
DR   PRINTS; PR00273; GALANIN.
DR   PROSITE; PS00861; GALANIN; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Neuropeptide;
KW   Reference proteome; Secreted.
FT   PEPTIDE         1..29
FT                   /note="Galanin"
FT                   /id="PRO_0000043872"
FT   MOD_RES         29
FT                   /note="Alanine amide"
FT                   /evidence="ECO:0000269|PubMed:1724081"
SQ   SEQUENCE   29 AA;  3186 MW;  F718719B2D3FB089 CRC64;
     GWTLNSAGYL LGPHAIDNHR SFHDKHGLA