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ALGF_PSEFL
ID   ALGF_PSEFL              Reviewed;         217 AA.
AC   P59791;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2003, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Alginate biosynthesis protein AlgF;
DE   Flags: Precursor;
GN   Name=algF;
OS   Pseudomonas fluorescens.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=294;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 17397 / DSM 50091 / CIP 73.25 / NCIMB 10525 / 12;
RX   PubMed=12775688; DOI=10.1128/jb.185.12.3515-3523.2003;
RA   Gimmestad M., Sletta H., Ertesvaag H., Bakkevig K., Jain S., Suh S.-J.,
RA   Skjaak-Braek G., Ellingsen T.E., Ohman D.E., Valla S.;
RT   "The Pseudomonas fluorescens AlgG protein, but not its mannuronan C-5-
RT   epimerase activity, is needed for alginate polymer formation.";
RL   J. Bacteriol. 185:3515-3523(2003).
CC   -!- FUNCTION: Together with AlgI and AlgJ, forms an inner membrane complex
CC       which probably interacts with the alginate polymerization-transport
CC       complex and adds acetyl groups at the O-2 and O-3 positions of
CC       mannuronate residues. Acetylation of alginate is important for the
CC       architecture of biofilms and increases the ability of alginate to act
CC       as a defense barrier (By similarity). {ECO:0000250}.
CC   -!- PATHWAY: Glycan biosynthesis; alginate biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AlgF family. {ECO:0000305}.
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DR   EMBL; AF527790; AAP46699.1; -; Genomic_DNA.
DR   RefSeq; WP_012722326.1; NZ_CABVHZ010000006.1.
DR   AlphaFoldDB; P59791; -.
DR   SMR; P59791; -.
DR   STRING; 690597.JH730920_gene1197; -.
DR   PATRIC; fig|294.129.peg.5010; -.
DR   eggNOG; ENOG5032T05; Bacteria.
DR   UniPathway; UPA00286; -.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0042121; P:alginic acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR035422; AlgF.
DR   Pfam; PF11182; AlgF; 1.
PE   3: Inferred from homology;
KW   Alginate biosynthesis; Periplasm; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..217
FT                   /note="Alginate biosynthesis protein AlgF"
FT                   /id="PRO_0000001116"
SQ   SEQUENCE   217 AA;  22808 MW;  7277C8D804C547F3 CRC64;
     MTFTTTPRRL AKTLALAAGM SVVSLSAFAG DAALYGPVAP KGSSFVRVYN ASNQEVSATV
     GSTNLSEVAP LASSDFSFMP GGDYSAKIGS QTVPVKLAAD HYYTLVNNSS GQPQLIEEPP
     FKNKQKSLVR VQNLSDKALT LKTADGKTDV VKSVAAKGRG EREINPVKVS LALYDGDKKV
     GDVKPVALER GEAAVLYVTG SGSSISPVWV KRPVSTR
 
 
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