ID   GALR_PSEPK              Reviewed;         397 AA.
AC   Q88JX7;
DT   05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=HTH-type transcriptional regulator GalR;
DE   AltName: Full=Gallate degradation protein R;
GN   Name=galR; OrderedLocusNames=PP_2516;
OS   Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS   / KT2440).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=160488;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440;
RX   PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA   Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA   Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA   Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F.,
RA   Madupu R., Nelson W.C., White O., Peterson J.D., Khouri H.M., Hance I.,
RA   Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A.,
RA   Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H.,
RA   Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C.,
RA   Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M.;
RT   "Complete genome sequence and comparative analysis of the metabolically
RT   versatile Pseudomonas putida KT2440.";
RL   Environ. Microbiol. 4:799-808(2002).
RN   [2]
RP   FUNCTION.
RC   STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440;
RX   PubMed=21219457; DOI=10.1111/j.1365-2958.2010.07448.x;
RA   Nogales J., Canales A., Jimenez-Barbero J., Serra B., Pingarron J.M.,
RA   Garcia J.L., Diaz E.;
RT   "Unravelling the gallic acid degradation pathway in bacteria: the gal
RT   cluster from Pseudomonas putida.";
RL   Mol. Microbiol. 79:359-374(2011).
CC   -!- FUNCTION: Transcriptional regulator for the galBCD and galTAP operons,
CC       encoding genes of the gallate degradation pathway.
CC       {ECO:0000269|PubMed:21219457}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; AE015451; AAN68128.1; -; Genomic_DNA.
DR   RefSeq; NP_744664.1; NC_002947.4.
DR   RefSeq; WP_010953450.1; NC_002947.4.
DR   AlphaFoldDB; Q88JX7; -.
DR   SMR; Q88JX7; -.
DR   STRING; 160488.PP_2516; -.
DR   EnsemblBacteria; AAN68128; AAN68128; PP_2516.
DR   KEGG; ppu:PP_2516; -.
DR   PATRIC; fig|160488.4.peg.2671; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_6_0_6; -.
DR   OMA; KCILPRA; -.
DR   PhylomeDB; Q88JX7; -.
DR   BioCyc; PPUT160488:G1G01-2700-MON; -.
DR   Proteomes; UP000000556; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 2.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 2.
DR   PROSITE; PS50931; HTH_LYSR; 2.
PE   3: Inferred from homology;
KW   Aromatic hydrocarbons catabolism; DNA-binding; Reference proteome; Repeat;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..397
FT                   /note="HTH-type transcriptional regulator GalR"
FT                   /id="PRO_0000418486"
FT   DOMAIN          7..64
FT                   /note="HTH lysR-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DOMAIN          99..156
FT                   /note="HTH lysR-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        24..43
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        116..135
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   397 AA;  43255 MW;  1372107AAF2027CF CRC64;
     MIDVELPNLM QVRAFIRVAE LGSVSRATEV LFRAQSVVTR AIAELEARFA VPLFERHANG
     MRLTDYGECL LPRAQRVLAE LDGVPSLLGT AQGEPLYLFQ ARRLQVFVKL CETRHMQTVA
     RHFGLSQPAV SAALKVLEGG CGQPLFVRTS RGLQPTVASR DILFPIRRAL NELRLLDSDL
     SAMQGTLRGV VHVGALPLGR SRILPDAILR FTAQHPQVRV VTNESPFDLL ATELRVGDVD
     FVLGALRPHD YASDLVGEPL INEEMVVLAR RGHPLLHTHL TLKGVHQARW VLPRAGSPAR
     QLLDNCFAAA GLTAPWPVVE SADLAVIRGL LVRSDMLAAV SAHQLAYEIA SGELQRLPLA
     LPGTARAIGL MQRSGCLQSP AAVALMACIR QVITEQA