ALGH_PSEAE
ID ALGH_PSEAE Reviewed; 189 AA.
AC Q9RQ16;
DT 26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=UPF0301 protein AlgH {ECO:0000255|HAMAP-Rule:MF_00758};
GN Name=algH; OrderedLocusNames=PA0405;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=8830;
RA Ledgham F., Latifi A., Schlictman D., Soscia C., Chakrabarty A.M.,
RA Lazdunski A., Foglino M.;
RT "Global regulation in Pseudomonas aeruginosa: alginate transcriptional
RT activators AlgR2 and AlgH act as repressors of quorum sensing.";
RL Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- SIMILARITY: Belongs to the UPF0301 (AlgH) family. {ECO:0000255|HAMAP-
CC Rule:MF_00758}.
CC -!- CAUTION: Is indicated by Ref.1 as being involved in the transcriptional
CC regulation of alginate biosynthesis. However, there is no evidence for
CC such function in proteins belonging to this family. {ECO:0000305}.
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DR EMBL; AF137022; AAD52846.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG03794.1; -; Genomic_DNA.
DR PIR; C83596; C83596.
DR RefSeq; NP_249096.1; NC_002516.2.
DR RefSeq; WP_003100947.1; NZ_QZGE01000016.1.
DR PDB; 2MUI; NMR; -; A=1-189.
DR PDBsum; 2MUI; -.
DR AlphaFoldDB; Q9RQ16; -.
DR BMRB; Q9RQ16; -.
DR SMR; Q9RQ16; -.
DR STRING; 287.DR97_3373; -.
DR PaxDb; Q9RQ16; -.
DR PRIDE; Q9RQ16; -.
DR DNASU; 878243; -.
DR EnsemblBacteria; AAG03794; AAG03794; PA0405.
DR GeneID; 878243; -.
DR KEGG; pae:PA0405; -.
DR PATRIC; fig|208964.12.peg.426; -.
DR PseudoCAP; PA0405; -.
DR HOGENOM; CLU_057596_1_0_6; -.
DR InParanoid; Q9RQ16; -.
DR OMA; IYWGGDF; -.
DR PhylomeDB; Q9RQ16; -.
DR BioCyc; PAER208964:G1FZ6-409-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR HAMAP; MF_00758; UPF0301; 1.
DR InterPro; IPR003774; UPF0301.
DR PANTHER; PTHR30327; PTHR30327; 1.
DR Pfam; PF02622; DUF179; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome.
FT CHAIN 1..189
FT /note="UPF0301 protein AlgH"
FT /id="PRO_0000214336"
FT STRAND 6..8
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 12..16
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 23..25
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 29..36
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 39..44
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 48..52
FT /evidence="ECO:0007829|PDB:2MUI"
FT HELIX 53..60
FT /evidence="ECO:0007829|PDB:2MUI"
FT HELIX 68..71
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 74..77
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 80..92
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 99..102
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 105..108
FT /evidence="ECO:0007829|PDB:2MUI"
FT HELIX 111..119
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 127..136
FT /evidence="ECO:0007829|PDB:2MUI"
FT HELIX 139..145
FT /evidence="ECO:0007829|PDB:2MUI"
FT STRAND 148..153
FT /evidence="ECO:0007829|PDB:2MUI"
FT HELIX 156..160
FT /evidence="ECO:0007829|PDB:2MUI"
FT HELIX 166..175
FT /evidence="ECO:0007829|PDB:2MUI"
FT HELIX 179..183
FT /evidence="ECO:0007829|PDB:2MUI"
SQ SEQUENCE 189 AA; 20212 MW; 848155FCCF8A7017 CRC64;
MKQSSPTYLK HHFLIAMPHM ADPNFAQTVT YLVEHNEQGA MGLVINRPSG LNLAEVLEQL
KPDALPPARC QHIDIYNGGP VQTDRGFVLH PSGLSYQSTL ELGELAMSTS QDVLFAIAAG
TGPEKSLISL GYAGWEAGQL EAELSDNAWL TCPADPAILF DLPPEERLSA AAARLGVNLS
LLTAQAGHA
