ID   GANOD_GANLU             Reviewed;          27 AA.
AC   P84995;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 16.
DE   RecName: Full=Ganodermin;
DE   Flags: Fragment;
OS   Ganoderma lucidum (Ling zhi medicinal fungus) (Bracket fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Polyporales; Polyporaceae; Ganoderma.
OX   NCBI_TaxID=5315;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND FUNCTION.
RC   TISSUE=Fruiting body {ECO:0000269|PubMed:16039755};
RX   PubMed=16039755; DOI=10.1016/j.peptides.2005.06.009;
RA   Wang H., Ng T.B.;
RT   "Ganodermin, an antifungal protein from fruiting bodies of the medicinal
RT   mushroom Ganoderma lucidum.";
RL   Peptides 27:27-30(2006).
CC   -!- FUNCTION: Has antifungal activity against B.cinera, F.oxysporum and
CC       P.piricola with IC(50) values of 15.2 uM, 12.4 uM and 18.1 uM,
CC       respectively. Lacks hemagglutinating activity towards rabbit
CC       erythrocytes. Lacks deoxyribonuclease, ribonuclease and protease
CC       inhibitory activities. {ECO:0000269|PubMed:16039755}.
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DR   AlphaFoldDB; P84995; -.
DR   GO; GO:0050832; P:defense response to fungus; IDA:UniProtKB.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antimicrobial; Direct protein sequencing; Fungicide.
FT   CHAIN           1..>27
FT                   /note="Ganodermin"
FT                   /id="PRO_0000252248"
FT   NON_TER         27
FT                   /evidence="ECO:0000303|PubMed:16039755"
SQ   SEQUENCE   27 AA;  2729 MW;  269BC0521548F1B2 CRC64;
     AGETHTVMIN HAGRGAPKLV VGGKKLS