ID   GAR1A_RAT               Reviewed;         295 AA.
AC   Q5RJN7;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Golgi associated RAB2 interactor protein 1A;
GN   Name=Garin1a; Synonyms=Fam137b, Fam71f2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-220; SER-221; SER-251 AND
RP   SER-255, AND IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- FUNCTION: RAB2B effector protein required for accurate acrosome
CC       formation and normal male fertility. {ECO:0000250|UniProtKB:B2RXB0}.
CC   -!- SUBUNIT: Interacts (via N-terminus) with RAB2B (in GTP-bound form).
CC       {ECO:0000250|UniProtKB:B2RXB0}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:B2RXB0}.
CC   -!- SIMILARITY: Belongs to the GARIN family. {ECO:0000305}.
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DR   EMBL; BC086566; AAH86566.1; -; mRNA.
DR   RefSeq; NP_001019494.1; NM_001024323.1.
DR   AlphaFoldDB; Q5RJN7; -.
DR   STRING; 10116.ENSRNOP00000057100; -.
DR   iPTMnet; Q5RJN7; -.
DR   PhosphoSitePlus; Q5RJN7; -.
DR   PaxDb; Q5RJN7; -.
DR   PRIDE; Q5RJN7; -.
DR   Ensembl; ENSRNOT00000060353; ENSRNOP00000057100; ENSRNOG00000039383.
DR   GeneID; 500060; -.
DR   KEGG; rno:500060; -.
DR   UCSC; RGD:1561814; rat.
DR   CTD; 346653; -.
DR   RGD; 1561814; Fam71f2.
DR   eggNOG; ENOG502S7XV; Eukaryota.
DR   GeneTree; ENSGT00940000162027; -.
DR   HOGENOM; CLU_069391_1_0_1; -.
DR   InParanoid; Q5RJN7; -.
DR   OMA; RIEFTHC; -.
DR   OrthoDB; 1360447at2759; -.
DR   PhylomeDB; Q5RJN7; -.
DR   TreeFam; TF336050; -.
DR   PRO; PR:Q5RJN7; -.
DR   Proteomes; UP000002494; Chromosome 4.
DR   Bgee; ENSRNOG00000039383; Expressed in testis.
DR   GO; GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
DR   GO; GO:0001675; P:acrosome assembly; ISS:UniProtKB.
DR   InterPro; IPR022168; DUF3699.
DR   Pfam; PF12480; DUF3699; 1.
PE   1: Evidence at protein level;
KW   Golgi apparatus; Phosphoprotein; Reference proteome.
FT   CHAIN           1..295
FT                   /note="Golgi associated RAB2 interactor protein 1A"
FT                   /id="PRO_0000311690"
FT   REGION          187..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         220
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         221
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         251
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         255
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
SQ   SEQUENCE   295 AA;  32795 MW;  951A5874AA4E36D7 CRC64;
     MSKIRGLPPA IRDPGPGVEL GVENGLLCQL IHSPEFNLFS DSVVFESTFI QVTKQGNWMD
     AYERSATIIL GVTSSVPSLP LPNILLMANV TWPQGPFSTC STLGAPVITL SRILPLKYVE
     LQIYDRTQRI LRVRTVTEKI YYLRLHEKHP QAVFRFWIRL VKILQKGLSI TTKDPRIHFT
     HCLVPKMPNS STETTPESSR PASSQSSETI MLLAAERAGS SVLDLSNRHR FSEDRYTDTK
     TDNSSNCKTA SPVASLIGMP MRATLIHSLW EQEDSCETLL QAPVASSLGD NFLGP