ID   GAR1B_RAT               Reviewed;         344 AA.
AC   Q68FV5;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Golgi associated RAB2 interactor protein 1B {ECO:0000305};
GN   Name=Garin1b; Synonyms=Fam137a, Fam71f1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: RAB2B effector protein required for accurate acrosome
CC       formation and normal male fertility. In complex with RAB2A/RAB2B, seems
CC       to suppress excessive vesicle trafficking during acrosome formation.
CC       {ECO:0000250|UniProtKB:Q3UZD7}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250|UniProtKB:Q3UZD7}.
CC   -!- SIMILARITY: Belongs to the GARIN family. {ECO:0000305}.
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DR   EMBL; BC079297; AAH79297.1; -; mRNA.
DR   RefSeq; NP_001019495.1; NM_001024324.1.
DR   AlphaFoldDB; Q68FV5; -.
DR   STRING; 10116.ENSRNOP00000047959; -.
DR   PaxDb; Q68FV5; -.
DR   GeneID; 500061; -.
DR   KEGG; rno:500061; -.
DR   UCSC; RGD:1564147; rat.
DR   CTD; 84691; -.
DR   RGD; 1564147; Fam71f1.
DR   eggNOG; ENOG502S7XV; Eukaryota.
DR   InParanoid; Q68FV5; -.
DR   PhylomeDB; Q68FV5; -.
DR   PRO; PR:Q68FV5; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
DR   GO; GO:0001675; P:acrosome assembly; ISS:UniProtKB.
DR   GO; GO:0007340; P:acrosome reaction; ISS:UniProtKB.
DR   InterPro; IPR022168; DUF3699.
DR   Pfam; PF12480; DUF3699; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Reference proteome.
FT   CHAIN           1..344
FT                   /note="Golgi associated RAB2 interactor protein 1B"
FT                   /id="PRO_0000311688"
SQ   SEQUENCE   344 AA;  38996 MW;  C21F858B1813E108 CRC64;
     MMTSVPPRKT WWKSKKTVKV RRSYSTFPSL NAWEKFRGLL PVDGETNPGV GLGVEEGLLC
     QMVHSPEFNL FPNSVVFESN FVQVRRSRDW KEIYKASNTM ALGVTSSVPC LPLPNILLMA
     RVIWHQGQSQ TWNRPSTVPS INLKSILPLK FVELQIWDHH ERILRLRTVT EKIYFLKLHP
     DHPETVFRFW IRLVQILHKG LSITTKDPTI LVTHCLVPKS LCSPGGKSEL VQKNSKGLQP
     SESLTHLMAQ GESEALSQIF SDLHQQKQYS SSRSEKVQIN KTSSEKATPC EDSIPCTCDL
     NWRDAFMFGE WERENPSGPQ PHSLLSTLAA SSRPRLSLIG GNSI