GAR2_BOVIN
ID GAR2_BOVIN Reviewed; 397 AA.
AC Q2YDE8;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Golgi associated RAB2 interactor protein 2;
GN Name=GARIN2; Synonyms=FAM71D;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Seems to play a role in sperm motility.
CC {ECO:0000250|UniProtKB:D3YV92}.
CC -!- SUBUNIT: Interacts with CALM1. {ECO:0000250|UniProtKB:D3YV92}.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000250|UniProtKB:D3YV92}. Note=In mature sperm, localizes in the
CC midpiece of flagella. {ECO:0000250|UniProtKB:D3YV92}.
CC -!- SIMILARITY: Belongs to the GARIN family. {ECO:0000305}.
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DR EMBL; BC110256; AAI10257.1; -; mRNA.
DR RefSeq; NP_001040090.1; NM_001046625.1.
DR AlphaFoldDB; Q2YDE8; -.
DR STRING; 9913.ENSBTAP00000040913; -.
DR PaxDb; Q2YDE8; -.
DR PRIDE; Q2YDE8; -.
DR GeneID; 618905; -.
DR KEGG; bta:618905; -.
DR CTD; 161142; -.
DR eggNOG; ENOG502S1VC; Eukaryota.
DR InParanoid; Q2YDE8; -.
DR OrthoDB; 1402381at2759; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0097225; C:sperm midpiece; ISS:UniProtKB.
DR GO; GO:0030317; P:flagellated sperm motility; ISS:UniProtKB.
DR InterPro; IPR022168; DUF3699.
DR Pfam; PF12480; DUF3699; 1.
PE 2: Evidence at transcript level;
KW Cell projection; Cilium; Flagellum; Reference proteome.
FT CHAIN 1..397
FT /note="Golgi associated RAB2 interactor protein 2"
FT /id="PRO_0000261632"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..397
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 397 AA; 44289 MW; DC8B408F09A8FDEA CRC64;
MKKSNRKSPT RIDEKDDICV PDSKDPGELQ NMLNGGEYAP FVSPPILESN FIQVNRRGES
IYLHNRANWV TVGICSSNPT TKTPNVMLLA HLTPTAQKDS EPLFTSLLTS PSPENLVLTR
FLPLQFVTLS VHDAENMRIK VKLVSGRAYY LQLCAPACKQ EALFCQWVEL ISLLNKEKAK
ASKVSEVSSL SEITNSTDIT GSVDIMDIAA FPAIQTSHLS TCSDPNNDVE SVDFSEFTDI
TDVTDDTDIP ENEVTEAPDI NIVTEVTEVT DICGVTASSG VRVVFENDDI LKAKQEEKEK
MENILKSGCL RDTKSKNEFR ESPKRVTISN LALTFEGERC FQTTLTPEED ETEKSKEMSD
RPREIRTMDS ESTTLKAEEP RSRRTDSDTS DKCKLLN