GASA5_ARATH
ID GASA5_ARATH Reviewed; 97 AA.
AC Q84J95;
DT 16-NOV-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Gibberellin-regulated protein 5;
DE AltName: Full=GAST1 protein homolog 5;
DE Flags: Precursor;
GN Name=GASA5; OrderedLocusNames=At3g02885; ORFNames=F13E7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=19190987; DOI=10.1007/s11103-009-9452-7;
RA Zhang S., Yang C., Peng J., Sun S., Wang X.;
RT "GASA5, a regulator of flowering time and stem growth in Arabidopsis
RT thaliana.";
RL Plant Mol. Biol. 69:745-759(2009).
RN [5]
RP FUNCTION.
RX PubMed=21835493; DOI=10.1016/j.jplph.2011.06.010;
RA Zhang S., Wang X.;
RT "Overexpression of GASA5 increases the sensitivity of Arabidopsis to heat
RT stress.";
RL J. Plant Physiol. 168:2093-2101(2011).
CC -!- FUNCTION: Gibberellin-regulated protein that acts as a negative
CC regulator of gibberellin-induced flowering and stem growth. May inhibit
CC flowering and inflorescence growth via a pathway involving GAI and by
CC enhancing FLC expression and repressing FT and LFY. Acts as a negative
CC regulator in thermotolerance by resogulating both salicylic acid (SA)
CC signaling and heat shock-protein accumulation.
CC {ECO:0000269|PubMed:19190987, ECO:0000269|PubMed:21835493}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19190987}. Secreted,
CC cell wall {ECO:0000269|PubMed:19190987}. Secreted, extracellular space,
CC extracellular matrix {ECO:0000269|PubMed:19190987}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, root hairs, vasculature of
CC cotyledons and hypocotyls, shoot apex, leaf veins, stems, flower
CC receptacles, pollen, filaments, anthers and siliques.
CC {ECO:0000269|PubMed:19190987}.
CC -!- INDUCTION: Down-regulated by gibberellin.
CC {ECO:0000269|PubMed:19190987}.
CC -!- PTM: Six disulfide bonds may be present.
CC -!- DISRUPTION PHENOTYPE: Early flowering. {ECO:0000269|PubMed:19190987}.
CC -!- SIMILARITY: Belongs to the GASA family. {ECO:0000305}.
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DR EMBL; AC018363; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002686; AEE73874.1; -; Genomic_DNA.
DR EMBL; BT002786; AAO22614.1; -; mRNA.
DR EMBL; BT004355; AAO42349.1; -; mRNA.
DR RefSeq; NP_566186.1; NM_111158.4.
DR AlphaFoldDB; Q84J95; -.
DR SMR; Q84J95; -.
DR BioGRID; 6527; 1.
DR IntAct; Q84J95; 1.
DR STRING; 3702.AT3G02885.1; -.
DR PaxDb; Q84J95; -.
DR PRIDE; Q84J95; -.
DR ProteomicsDB; 247391; -.
DR EnsemblPlants; AT3G02885.1; AT3G02885.1; AT3G02885.
DR GeneID; 821194; -.
DR Gramene; AT3G02885.1; AT3G02885.1; AT3G02885.
DR KEGG; ath:AT3G02885; -.
DR Araport; AT3G02885; -.
DR TAIR; locus:505006327; AT3G02885.
DR eggNOG; ENOG502S3SC; Eukaryota.
DR HOGENOM; CLU_142643_5_0_1; -.
DR InParanoid; Q84J95; -.
DR OMA; RSYSPIM; -.
DR OrthoDB; 1589358at2759; -.
DR PhylomeDB; Q84J95; -.
DR PRO; PR:Q84J95; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q84J95; baseline and differential.
DR Genevisible; Q84J95; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0009740; P:gibberellic acid mediated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0010286; P:heat acclimation; IMP:TAIR.
DR GO; GO:0009408; P:response to heat; IMP:TAIR.
DR GO; GO:0009751; P:response to salicylic acid; IMP:TAIR.
DR InterPro; IPR003854; GASA.
DR Pfam; PF02704; GASA; 1.
PE 2: Evidence at transcript level;
KW Cell wall; Disulfide bond; Extracellular matrix;
KW Gibberellin signaling pathway; Reference proteome; Secreted; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..97
FT /note="Gibberellin-regulated protein 5"
FT /id="PRO_0000413703"
SQ SEQUENCE 97 AA; 10845 MW; DBAC85C257A0CE07 CRC64;
MANCIRRNAL FFLTLLFLLS VSNLVQAARG GGKLKPQQCN SKCSFRCSAT SHKKPCMFFC
LKCCKKCLCV PPGTFGNKQT CPCYNNWKTK EGRPKCP
