GASBP_PSEAE
ID GASBP_PSEAE Reviewed; 302 AA.
AC Q9I402;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=L-glutamate/L-aspartate-binding protein {ECO:0000305};
DE Flags: Precursor;
GN OrderedLocusNames=PA1342 {ECO:0000312|EMBL:AAG04731.1};
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
RN [2]
RP FUNCTION AS A BINDING PROTEIN.
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=31627455; DOI=10.3390/ijms20205156;
RA Fernandez M., Rico-Jimenez M., Ortega A., Daddaoua A., Garcia Garcia A.I.,
RA Martin-Mora D., Torres N.M., Tajuelo A., Matilla M.A., Krell T.;
RT "Determination of Ligand Profiles for Pseudomonas aeruginosa Solute Binding
RT Proteins.";
RL Int. J. Mol. Sci. 20:5156-5156(2019).
CC -!- FUNCTION: Binds L-glutamate and L-aspartate.
CC {ECO:0000269|PubMed:31627455}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 3 family.
CC {ECO:0000305}.
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DR EMBL; AE004091; AAG04731.1; -; Genomic_DNA.
DR PIR; H83478; H83478.
DR RefSeq; NP_250033.1; NC_002516.2.
DR RefSeq; WP_003082770.1; NZ_QZGE01000005.1.
DR AlphaFoldDB; Q9I402; -.
DR SMR; Q9I402; -.
DR STRING; 287.DR97_452; -.
DR TCDB; 3.A.1.3.22; the atp-binding cassette (abc) superfamily.
DR PaxDb; Q9I402; -.
DR PRIDE; Q9I402; -.
DR DNASU; 879321; -.
DR EnsemblBacteria; AAG04731; AAG04731; PA1342.
DR GeneID; 879321; -.
DR KEGG; pae:PA1342; -.
DR PATRIC; fig|208964.12.peg.1394; -.
DR PseudoCAP; PA1342; -.
DR HOGENOM; CLU_019602_0_0_6; -.
DR InParanoid; Q9I402; -.
DR OMA; PNQLDCL; -.
DR PhylomeDB; Q9I402; -.
DR BioCyc; PAER208964:G1FZ6-1368-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005615; C:extracellular space; IDA:PseudoCAP.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IBA:GO_Central.
DR GO; GO:0042940; P:D-amino acid transport; IMP:PseudoCAP.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR Pfam; PF00497; SBP_bac_3; 1.
DR SMART; SM00062; PBPb; 1.
PE 1: Evidence at protein level;
KW Amino-acid transport; Periplasm; Reference proteome; Signal; Transport.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..302
FT /note="L-glutamate/L-aspartate-binding protein"
FT /evidence="ECO:0000255"
FT /id="PRO_5004327455"
SQ SEQUENCE 302 AA; 33054 MW; 1E217D4F28AEFF47 CRC64;
MRIAPSLLST AIVAALLSAP VVADELTGTL KKIKETGTIT LGHRDASIPF SYLGTEPGKP
IGYSHDLQLK VVEAVKKELN LPELKVRYNL VTSQTRIPLV QNGTVDIECG STTNNEERQK
QVDFSVGIFE VGTRLLSKKT ANIKDFDDLK GKNVVTTAGT TSERLLKAMN ADKKMGMNII
SAKDHGESFM MLESGRAVAF MMDDALLYGE MAKAKKPDDW VVGGTPQSFE IYGCMVRKGD
AAFKKVVDKA ITDTYASGEV NKIYDKWFTQ PIPPKGLNLN FPMSEELKKL IASPTDKAAE
QM
