GASP2_HUMAN
ID GASP2_HUMAN Reviewed; 838 AA.
AC Q96D09; D3DXA0; Q8NAB4;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 161.
DE RecName: Full=G-protein coupled receptor-associated sorting protein 2;
DE Short=GASP-2;
GN Name=GPRASP2;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15772651; DOI=10.1038/nature03440;
RA Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA Rogers J., Bentley D.R.;
RT "The DNA sequence of the human X chromosome.";
RL Nature 434:325-337(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Lung, and Ovary;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 657-838.
RC TISSUE=Kidney, and Spleen;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [5]
RP FUNCTION, TISSUE SPECIFICITY, AND INTERACTION WITH G PROTEIN-COUPLED
RP RECEPTORS.
RX PubMed=15086532; DOI=10.1111/j.1471-4159.2004.02411.x;
RA Simonin F., Karcher P., Boeuf J.J.-M., Matifas A., Kieffer B.L.;
RT "Identification of a novel family of G protein-coupled receptor associated
RT sorting proteins.";
RL J. Neurochem. 89:766-775(2004).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Erythroleukemia;
RX PubMed=23186163; DOI=10.1021/pr300630k;
RA Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA Mohammed S.;
RT "Toward a comprehensive characterization of a human cancer cell
RT phosphoproteome.";
RL J. Proteome Res. 12:260-271(2013).
RN [7]
RP INVOLVEMENT IN DFNX7, AND VARIANT DFNX7 ASN-573.
RX PubMed=28096187; DOI=10.1136/jmedgenet-2016-104320;
RA Xing G., Yao J., Liu C., Wei Q., Qian X., Wu L., Lu Y., Cao X.;
RT "GPRASP2, a novel causative gene mutated in an X-linked recessive syndromic
RT hearing loss.";
RL J. Med. Genet. 54:426-430(2017).
CC -!- FUNCTION: May play a role in regulation of a variety of G-protein
CC coupled receptors. {ECO:0000269|PubMed:15086532}.
CC -!- SUBUNIT: Interacts with cytoplasmic tails of a variety of G-protein
CC coupled receptors such as muscarinic acetylcholine receptor M1/CHRM1
CC and calcitonin receptor/CALCR. {ECO:0000269|PubMed:15086532}.
CC -!- INTERACTION:
CC Q96D09; Q969G5: CAVIN3; NbExp=3; IntAct=EBI-473189, EBI-3893101;
CC Q96D09; Q9HC52: CBX8; NbExp=6; IntAct=EBI-473189, EBI-712912;
CC Q96D09; Q8IYE0: CCDC146; NbExp=3; IntAct=EBI-473189, EBI-10749669;
CC Q96D09; Q8IYR0: CFAP206; NbExp=6; IntAct=EBI-473189, EBI-749051;
CC Q96D09; Q8N7B9-2: EFCAB3; NbExp=3; IntAct=EBI-473189, EBI-11958551;
CC Q96D09; A0A0S2Z6B0: EFHA1; NbExp=3; IntAct=EBI-473189, EBI-16439972;
CC Q96D09; Q9H5Z6-2: FAM124B; NbExp=3; IntAct=EBI-473189, EBI-11986315;
CC Q96D09; O94868-3: FCHSD2; NbExp=3; IntAct=EBI-473189, EBI-11958845;
CC Q96D09; Q9NU39: FOXD4L1; NbExp=3; IntAct=EBI-473189, EBI-11320806;
CC Q96D09; Q8TAE8: GADD45GIP1; NbExp=3; IntAct=EBI-473189, EBI-372506;
CC Q96D09; Q5SUL5: HLA-A; NbExp=3; IntAct=EBI-473189, EBI-8561769;
CC Q96D09; P42858: HTT; NbExp=5; IntAct=EBI-473189, EBI-466029;
CC Q96D09; Q8TAP4-4: LMO3; NbExp=3; IntAct=EBI-473189, EBI-11742507;
CC Q96D09; Q8NHZ7: MBD3L2; NbExp=3; IntAct=EBI-473189, EBI-11989378;
CC Q96D09; Q8WWB5: PIH1D2; NbExp=3; IntAct=EBI-473189, EBI-10232538;
CC Q96D09; Q5JTB6: PLAC9; NbExp=3; IntAct=EBI-473189, EBI-3923605;
CC Q96D09; O43395: PRPF3; NbExp=3; IntAct=EBI-473189, EBI-744322;
CC Q96D09; Q9UJ41-4: RABGEF1; NbExp=3; IntAct=EBI-473189, EBI-14093916;
CC Q96D09; Q96EN9: REX1BD; NbExp=3; IntAct=EBI-473189, EBI-745810;
CC Q96D09; Q8TCX5: RHPN1; NbExp=3; IntAct=EBI-473189, EBI-746325;
CC Q96D09; O76064: RNF8; NbExp=3; IntAct=EBI-473189, EBI-373337;
CC Q96D09; Q86UD0: SAPCD2; NbExp=3; IntAct=EBI-473189, EBI-2561646;
CC Q96D09; Q15047-2: SETDB1; NbExp=3; IntAct=EBI-473189, EBI-9090795;
CC Q96D09; Q9BYH1-5: SEZ6L; NbExp=3; IntAct=EBI-473189, EBI-12012146;
CC Q96D09; Q9H788: SH2D4A; NbExp=3; IntAct=EBI-473189, EBI-747035;
CC Q96D09; Q8WXA9: SREK1; NbExp=3; IntAct=EBI-473189, EBI-1044237;
CC Q96D09; Q969Z0: TBRG4; NbExp=3; IntAct=EBI-473189, EBI-702328;
CC Q96D09; Q9BQ70: TCF25; NbExp=8; IntAct=EBI-473189, EBI-745182;
CC Q96D09; Q5W5X9-3: TTC23; NbExp=3; IntAct=EBI-473189, EBI-9090990;
CC Q96D09; Q99757: TXN2; NbExp=4; IntAct=EBI-473189, EBI-2932492;
CC Q96D09; A0A024R8A9: USP20; NbExp=3; IntAct=EBI-473189, EBI-14096082;
CC Q96D09; P61981: YWHAG; NbExp=3; IntAct=EBI-473189, EBI-359832;
CC Q96D09; Q53FD0-2: ZC2HC1C; NbExp=3; IntAct=EBI-473189, EBI-14104088;
CC Q96D09; Q68DK2-5: ZFYVE26; NbExp=3; IntAct=EBI-473189, EBI-8656416;
CC Q96D09; A0A0S2Z5X4: ZNF688; NbExp=3; IntAct=EBI-473189, EBI-16429014;
CC Q96D09; Q5W150; NbExp=3; IntAct=EBI-473189, EBI-10248148;
CC -!- TISSUE SPECIFICITY: Expressed in the brain.
CC {ECO:0000269|PubMed:15086532}.
CC -!- DISEASE: Deafness, X-linked, 7 (DFNX7) [MIM:301018]: A congenital form
CC of bilateral mixed or conductive hearing loss, which is progressive in
CC some patients. Additional clinical features include ear anomalies and
CC facial dysmorphism with bilateral ptosis.
CC {ECO:0000269|PubMed:28096187}. Note=The disease is caused by variants
CC affecting the gene represented in this entry.
CC -!- SIMILARITY: Belongs to the GPRASP family. {ECO:0000305}.
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DR EMBL; AL035427; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471190; EAW54727.1; -; Genomic_DNA.
DR EMBL; CH471190; EAW54728.1; -; Genomic_DNA.
DR EMBL; CH471190; EAW54729.1; -; Genomic_DNA.
DR EMBL; BC013576; AAH13576.1; -; mRNA.
DR EMBL; BC036772; AAH36772.1; -; mRNA.
DR EMBL; AK092981; -; NOT_ANNOTATED_CDS; mRNA.
DR CCDS; CCDS14501.1; -.
DR RefSeq; NP_001004051.1; NM_001004051.3.
DR RefSeq; NP_001171803.1; NM_001184874.2.
DR RefSeq; NP_001171804.1; NM_001184875.2.
DR RefSeq; NP_001171805.1; NM_001184876.2.
DR RefSeq; NP_001186747.1; NM_001199818.1.
DR RefSeq; NP_612446.1; NM_138437.5.
DR AlphaFoldDB; Q96D09; -.
DR SMR; Q96D09; -.
DR BioGRID; 125399; 116.
DR BioGRID; 1529361; 2.
DR IntAct; Q96D09; 75.
DR MINT; Q96D09; -.
DR STRING; 9606.ENSP00000437872; -.
DR iPTMnet; Q96D09; -.
DR PhosphoSitePlus; Q96D09; -.
DR BioMuta; GPRASP2; -.
DR DMDM; 74751808; -.
DR EPD; Q96D09; -.
DR jPOST; Q96D09; -.
DR MassIVE; Q96D09; -.
DR MaxQB; Q96D09; -.
DR PaxDb; Q96D09; -.
DR PeptideAtlas; Q96D09; -.
DR PRIDE; Q96D09; -.
DR ProteomicsDB; 76244; -.
DR Antibodypedia; 351; 197 antibodies from 28 providers.
DR DNASU; 114928; -.
DR Ensembl; ENST00000332262.10; ENSP00000339057.3; ENSG00000158301.20.
DR Ensembl; ENST00000483720.7; ENSP00000507692.1; ENSG00000158301.20.
DR Ensembl; ENST00000486814.2; ENSP00000508139.1; ENSG00000158301.20.
DR Ensembl; ENST00000535209.6; ENSP00000437394.1; ENSG00000158301.20.
DR Ensembl; ENST00000543253.6; ENSP00000437872.1; ENSG00000158301.20.
DR GeneID; 100528062; -.
DR GeneID; 114928; -.
DR KEGG; hsa:100528062; -.
DR KEGG; hsa:114928; -.
DR MANE-Select; ENST00000483720.7; ENSP00000507692.1; NM_001004051.4; NP_001004051.1.
DR UCSC; uc004ejm.3; human.
DR CTD; 100528062; -.
DR CTD; 114928; -.
DR DisGeNET; 100528062; -.
DR DisGeNET; 114928; -.
DR GeneCards; GPRASP2; -.
DR HGNC; HGNC:25169; GPRASP2.
DR HPA; ENSG00000158301; Low tissue specificity.
DR MalaCards; GPRASP2; -.
DR MIM; 300969; gene.
DR MIM; 301018; phenotype.
DR neXtProt; NX_Q96D09; -.
DR OpenTargets; ENSG00000158301; -.
DR Orphanet; 500188; X-linked external auditory canal atresia-dilated internal auditory canal-facial dysmorphism syndrome.
DR PharmGKB; PA134976848; -.
DR VEuPathDB; HostDB:ENSG00000158301; -.
DR eggNOG; ENOG502S6CE; Eukaryota.
DR GeneTree; ENSGT00940000162726; -.
DR HOGENOM; CLU_017437_0_0_1; -.
DR InParanoid; Q96D09; -.
DR OMA; WPREEAN; -.
DR OrthoDB; 860703at2759; -.
DR PhylomeDB; Q96D09; -.
DR TreeFam; TF335652; -.
DR PathwayCommons; Q96D09; -.
DR SignaLink; Q96D09; -.
DR BioGRID-ORCS; 100528062; 11 hits in 159 CRISPR screens.
DR BioGRID-ORCS; 114928; 11 hits in 698 CRISPR screens.
DR GeneWiki; GPRASP2; -.
DR Pharos; Q96D09; Tbio.
DR PRO; PR:Q96D09; -.
DR Proteomes; UP000005640; Chromosome X.
DR RNAct; Q96D09; protein.
DR Bgee; ENSG00000158301; Expressed in endothelial cell and 181 other tissues.
DR Genevisible; Q96D09; HS.
DR GO; GO:0005737; C:cytoplasm; IDA:LIFEdb.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IDA:MGI.
DR GO; GO:0001540; F:amyloid-beta binding; IEA:Ensembl.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IDA:MGI.
DR GO; GO:0061484; P:hematopoietic stem cell homeostasis; IEA:Ensembl.
DR Gene3D; 1.25.10.10; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR006911; ARM-rpt_dom.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR043374; BHLHb9/GASP-1/GASP-2.
DR PANTHER; PTHR46414; PTHR46414; 1.
DR Pfam; PF04826; Arm_2; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 1: Evidence at protein level;
KW Deafness; Disease variant; Phosphoprotein; Reference proteome.
FT CHAIN 1..838
FT /note="G-protein coupled receptor-associated sorting
FT protein 2"
FT /id="PRO_0000239053"
FT REGION 1..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 349..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 282
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8BUY8"
FT MOD_RES 284
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8BUY8"
FT VARIANT 173
FT /note="R -> S (in dbSNP:rs6616421)"
FT /id="VAR_049265"
FT VARIANT 573
FT /note="A -> N (in DFNX7; requires 2 nucleotide
FT substitutions)"
FT /evidence="ECO:0000269|PubMed:28096187"
FT /id="VAR_081645"
SQ SEQUENCE 838 AA; 93773 MW; 2D30515916B7EACE CRC64;
MTGAEIEPSA QAKPEKKAGE EVIAGPEREN DVPLVVRPKV RTQATTGARP KTETKSVPAA
RPKTEAQAMS GARPKTEVQV MGGARPKTEA QGITGARPKT DARAVGGARS KTDAKAIPGA
RPKDEAQAWA QSEFGTEAVS QAEGVSQTNA VAWPLATAES GSVTKSKGLS MDRELVNVDA
ETFPGTQGQK GIQPWFGPGE ETNMGSWCYS RPRAREEASN ESGFWSADET STASSFWTGE
ETSVRSWPRE ESNTRSRHRA KHQTNPRSRP RSKQEAYVDS WSGSEDEASN PFSFWVGENT
NNLFRPRVRE EANIRSKLRT NREDCFESES EDEFYKQSWV LPGEEANSRF RHRDKEDPNT
ALKLRAQKDV DSDRVKQEPR FEEEVIIGSW FWAEKEASLE GGASAICESE PGTEEGAIGG
SAYWAEEKSS LGAVAREEAK PESEEEAIFG SWFWDRDEAC FDLNPCPVYK VSDRFRDAAE
ELNASSRPQT WDEVTVEFKP GLFHGVGFRS TSPFGIPEEA SEMLEAKPKN LELSPEGEEQ
ESLLQPDQPS PEFTFQYDPS YRSVREIREH LRARESAESE SWSCSCIQCE LKIGSEEFEE
FLLLMDKIRD PFIHEISKIA MGMRSASQFT RDFIRDSGVV SLIETLLNYP SSRVRTSFLE
NMIHMAPPYP NLNMIETFIC QVCEETLAHS VDSLEQLTGI RMLRHLTMTI DYHTLIANYM
SGFLSLLTTA NARTKFHVLK MLLNLSENPA VAKKLFSAKA LSIFVGLFNI EETNDNIQIV
IKMFQNISNI IKSGKMSLID DDFSLEPLIS AFREFEELAK QLQAQIDNQN DPEVGQQS
