GAT19_ARATH
ID GAT19_ARATH Reviewed; 211 AA.
AC Q6QPM2; A1A6I6; A3E4C0; C0SVL8; O23219;
DT 10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 2.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=GATA transcription factor 19 {ECO:0000303|PubMed:15084732};
DE AltName: Full=Protein HAN-LIKE 2 {ECO:0000303|PubMed:17208962};
GN Name=GATA19 {ECO:0000303|PubMed:15084732};
GN Synonyms=HANL2 {ECO:0000303|PubMed:17208962};
GN OrderedLocusNames=At4g36620 {ECO:0000312|Araport:AT4G36620};
GN ORFNames=C7A10.740 {ECO:0000312|EMBL:CAB80328.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17208962; DOI=10.1104/pp.106.090761;
RA Manfield I.W., Devlin P.F., Jen C.-H., Westhead D.R., Gilmartin P.M.;
RT "Conservation, convergence, and divergence of light-responsive, circadian-
RT regulated, and tissue-specific expression patterns during evolution of the
RT Arabidopsis GATA gene family.";
RL Plant Physiol. 143:941-958(2007).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Fujita M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9461215; DOI=10.1038/35140;
RA Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C.,
RA Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L., Ridley P.,
RA Hudson S.-A., Patel K., Murphy G., Piffanelli P., Wedler H., Wedler E.,
RA Wambutt R., Weitzenegger T., Pohl T., Terryn N., Gielen J., Villarroel R.,
RA De Clercq R., van Montagu M., Lecharny A., Aubourg S., Gy I., Kreis M.,
RA Lao N., Kavanagh T., Hempel S., Kotter P., Entian K.-D., Rieger M.,
RA Schaefer M., Funk B., Mueller-Auer S., Silvey M., James R., Monfort A.,
RA Pons A., Puigdomenech P., Douka A., Voukelatou E., Milioni D.,
RA Hatzopoulos P., Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A.,
RA Moores T., Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S.,
RA Ansorge W., Cooke R., Berger C., Delseny M., Voet M., Volckaert G.,
RA Mewes H.-W., Klosterman S., Schueller C., Chalwatzis N.;
RT "Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis
RT thaliana.";
RL Nature 391:485-488(1998).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-201.
RC STRAIN=cv. Columbia;
RX PubMed=14871304; DOI=10.1111/j.0960-7412.2003.01999.x;
RA Comai L., Young K., Till B.J., Reynolds S.H., Greene E.A., Codomo C.A.,
RA Enns L.C., Johnson J.E., Burtner C., Odden A.R., Henikoff S.;
RT "Efficient discovery of DNA polymorphisms in natural populations by
RT Ecotilling.";
RL Plant J. 37:778-786(2004).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia, cv. Landsberg erecta, and cv. Wassilewskija;
RX PubMed=15367721; DOI=10.1105/tpc.104.024869;
RA Zhao Y., Medrano L., Ohashi K., Fletcher J.C., Yu H., Sakai H.,
RA Meyerowitz E.M.;
RT "HANABA TARANU is a GATA transcription factor that regulates shoot apical
RT meristem and flower development in Arabidopsis.";
RL Plant Cell 16:2586-2600(2004).
RN [9]
RP GENE FAMILY ORGANIZATION.
RX PubMed=15084732; DOI=10.1104/pp.103.037788;
RA Reyes J.C., Muro-Pastor M.I., Florencio F.J.;
RT "The GATA family of transcription factors in Arabidopsis and rice.";
RL Plant Physiol. 134:1718-1732(2004).
RN [10]
RP FUNCTION, DISRUPTION PHENOTYPE, REPRESSION BY HAN, INTERACTION WITH GATA18,
RP AND DEVELOPMENTAL STAGE.
RX PubMed=23335616; DOI=10.1105/tpc.112.107854;
RA Zhang X., Zhou Y., Ding L., Wu Z., Liu R., Meyerowitz E.M.;
RT "Transcription repressor HANABA TARANU controls flower development by
RT integrating the actions of multiple hormones, floral organ specification
RT genes, and GATA3 family genes in Arabidopsis.";
RL Plant Cell 25:83-101(2013).
RN [11]
RP FUNCTION.
RX PubMed=25077795; DOI=10.1104/pp.114.246660;
RA Behringer C., Bastakis E., Ranftl Q.L., Mayer K.F., Schwechheimer C.;
RT "Functional diversification within the family of B-GATA transcription
RT factors through the leucine-leucine-methionine domain.";
RL Plant Physiol. 166:293-305(2014).
CC -!- FUNCTION: Transcriptional regulator that specifically binds 5'-GATA-3'
CC or 5'-GAT-3' motifs within gene promoters. Regulates both flower and
CC shoot apical meristem (SAM) development, especially for establishing
CC organ boundaries in shoots and flowers, probably by controlling the
CC number and position of WUS-expressing cells (PubMed:23335616,
CC PubMed:25077795). {ECO:0000250, ECO:0000269|PubMed:23335616,
CC ECO:0000269|PubMed:25077795}.
CC -!- SUBUNIT: Forms heterodimers with GATA18. {ECO:0000269|PubMed:23335616}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Expressed throughout the inflorescence meristem
CC (IM) and early stages of floral primordia. In developing flowers,
CC restricted to the innert hree whorls, speci fi cally in the petals,
CC stamens, and carpels. Within the stamens, mostly detected in the anther
CC locules as well as in the vascular strands. In carpels, mainly present
CC in ovules. {ECO:0000269|PubMed:23335616}.
CC -!- INDUCTION: Repressed by HAN. {ECO:0000269|PubMed:23335616}.
CC -!- DISRUPTION PHENOTYPE: Effects on sepal fusion, petal number, fertility
CC defects, and carpel abnormality. {ECO:0000269|PubMed:23335616}.
CC -!- SIMILARITY: Belongs to the type IV zinc-finger family. Class B
CC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DQ875130; ABL73200.1; -; mRNA.
DR EMBL; AB493721; BAH30559.1; -; mRNA.
DR EMBL; Z99708; CAB16831.1; -; Genomic_DNA.
DR EMBL; AL161589; CAB80328.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE86678.1; -; Genomic_DNA.
DR EMBL; BT029506; ABL66762.1; -; mRNA.
DR EMBL; AY530746; AAS45431.1; -; Genomic_DNA.
DR PIR; D85432; D85432.
DR RefSeq; NP_195380.1; NM_119825.3.
DR AlphaFoldDB; Q6QPM2; -.
DR SMR; Q6QPM2; -.
DR BioGRID; 15096; 12.
DR IntAct; Q6QPM2; 12.
DR STRING; 3702.AT4G36620.1; -.
DR PaxDb; Q6QPM2; -.
DR PRIDE; Q6QPM2; -.
DR EnsemblPlants; AT4G36620.1; AT4G36620.1; AT4G36620.
DR GeneID; 829814; -.
DR Gramene; AT4G36620.1; AT4G36620.1; AT4G36620.
DR KEGG; ath:AT4G36620; -.
DR Araport; AT4G36620; -.
DR TAIR; locus:2115195; AT4G36620.
DR eggNOG; KOG1601; Eukaryota.
DR HOGENOM; CLU_062129_1_0_1; -.
DR InParanoid; Q6QPM2; -.
DR OMA; SHTSNNM; -.
DR OrthoDB; 1472671at2759; -.
DR PhylomeDB; Q6QPM2; -.
DR PRO; PR:Q6QPM2; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q6QPM2; baseline and differential.
DR Genevisible; Q6QPM2; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009908; P:flower development; IMP:UniProtKB.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR044272; GATA18/19/20.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR46813; PTHR46813; 1.
DR Pfam; PF00320; GATA; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..211
FT /note="GATA transcription factor 19"
FT /id="PRO_0000083450"
FT ZN_FING 77..102
FT /note="GATA-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT REGION 111..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 211 AA; 23319 MW; EB2C17427254D092 CRC64;
MGFSMFFSPE NDVSHHSSPY ASVDCTLSLG TPSTRLCNED DERRFSSHTS DTIGWDFLNG
SKKGGGGGGH NLLARRCANC DTTSTPLWRN GPRGPKSLCN ACGIRFKKEE RRASTARNST
SGGGSTAAGV PTLDHQASAN YYYNNNNQYA SSSPWHHQHN TQRVPYYSPA NNEYSYVDDV
RVVDHDVTTD PFLSWRLNVA DRTGLVHDFT M
