GAT28_ARATH
ID GAT28_ARATH Reviewed; 302 AA.
AC Q8H1G0; Q94AN8; Q9C541;
DT 10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=GATA transcription factor 28;
DE AltName: Full=Protein TIFY 2A;
DE AltName: Full=ZIM-like 2 protein;
GN Name=GATA28; Synonyms=TIFY2A, ZML2; OrderedLocusNames=At1g51600;
GN ORFNames=F19C24.17, F5D21.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=14646219; DOI=10.1271/bbb.67.2495;
RA Shikata M., Takemura M., Yokota A., Kohchi T.;
RT "Arabidopsis ZIM, a plant-specific GATA factor, can function as a
RT transcriptional activator.";
RL Biosci. Biotechnol. Biochem. 67:2495-2497(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=14966217; DOI=10.1093/jxb/erh078;
RA Shikata M., Matsuda Y., Ando K., Nishii A., Takemura M., Yokota A.,
RA Kohchi T.;
RT "Characterization of Arabidopsis ZIM, a member of a novel plant-specific
RT GATA factor gene family.";
RL J. Exp. Bot. 55:631-639(2004).
RN [6]
RP GENE FAMILY ORGANIZATION.
RX PubMed=15084732; DOI=10.1104/pp.103.037788;
RA Reyes J.C., Muro-Pastor M.I., Florencio F.J.;
RT "The GATA family of transcription factors in Arabidopsis and rice.";
RL Plant Physiol. 134:1718-1732(2004).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17499004; DOI=10.1016/j.tplants.2007.04.004;
RA Vanholme B., Grunewald W., Bateman A., Kohchi T., Gheysen G.;
RT "The tify family previously known as ZIM.";
RL Trends Plant Sci. 12:239-244(2007).
CC -!- FUNCTION: Transcriptional activator that specifically binds 5'-GATA-3'
CC or 5'-GAT-3' motifs within gene promoters. {ECO:0000250,
CC ECO:0000269|PubMed:14966217}.
CC -!- INTERACTION:
CC Q8H1G0; Q9SGA0: ACR6; NbExp=4; IntAct=EBI-4435064, EBI-4425980;
CC Q8H1G0; A0A178WEI8: At1g54380; NbExp=3; IntAct=EBI-4435064, EBI-25520453;
CC Q8H1G0; Q9M2H8: At3g58380; NbExp=3; IntAct=EBI-4435064, EBI-4429615;
CC Q8H1G0; F4JI72: At4g03250; NbExp=3; IntAct=EBI-4435064, EBI-15192535;
CC Q8H1G0; O82617: BBX23; NbExp=4; IntAct=EBI-4435064, EBI-15191793;
CC Q8H1G0; Q9LNJ5: BHLH13; NbExp=6; IntAct=EBI-4435064, EBI-4434261;
CC Q8H1G0; O22265: CAO; NbExp=4; IntAct=EBI-4435064, EBI-780656;
CC Q8H1G0; Q93Z18: CKL3; NbExp=3; IntAct=EBI-4435064, EBI-4442347;
CC Q8H1G0; Q9ZT70: F9H3.4; NbExp=4; IntAct=EBI-4435064, EBI-25511123;
CC Q8H1G0; Q9ZVC9: FRS3; NbExp=4; IntAct=EBI-4435064, EBI-4448729;
CC Q8H1G0; Q8GXL7: GATA24; NbExp=9; IntAct=EBI-4435064, EBI-4426127;
CC Q8H1G0; Q9LRH6: GATA25; NbExp=9; IntAct=EBI-4435064, EBI-2460434;
CC Q8H1G0; Q8H1G0: GATA28; NbExp=3; IntAct=EBI-4435064, EBI-4435064;
CC Q8H1G0; Q8L4B2: NFYC9; NbExp=3; IntAct=EBI-4435064, EBI-2466050;
CC Q8H1G0; Q9FMC8: OFP13; NbExp=4; IntAct=EBI-4435064, EBI-15204858;
CC Q8H1G0; Q9S7H5: SCL21; NbExp=3; IntAct=EBI-4435064, EBI-1238472;
CC Q8H1G0; Q9FEE2: TON2; NbExp=3; IntAct=EBI-4435064, EBI-4452426;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Predominantly expressed in shoot apices,
CC inflorescences and roots. {ECO:0000269|PubMed:14966217}.
CC -!- SIMILARITY: Belongs to the type IV zinc-finger family. Class C
CC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG50873.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAG52620.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB119061; BAD02931.1; -; mRNA.
DR EMBL; AC024261; AAG52620.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC025294; AAG50873.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE32688.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32689.1; -; Genomic_DNA.
DR EMBL; AY045906; AAK76580.1; -; mRNA.
DR EMBL; AY150395; AAN12940.1; -; mRNA.
DR PIR; F96554; F96554.
DR RefSeq; NP_564593.1; NM_104038.4.
DR RefSeq; NP_974002.1; NM_202273.3.
DR AlphaFoldDB; Q8H1G0; -.
DR SMR; Q8H1G0; -.
DR BioGRID; 26810; 40.
DR IntAct; Q8H1G0; 40.
DR STRING; 3702.AT1G51600.1; -.
DR iPTMnet; Q8H1G0; -.
DR PaxDb; Q8H1G0; -.
DR PRIDE; Q8H1G0; -.
DR ProteomicsDB; 230482; -.
DR EnsemblPlants; AT1G51600.1; AT1G51600.1; AT1G51600.
DR EnsemblPlants; AT1G51600.2; AT1G51600.2; AT1G51600.
DR GeneID; 841585; -.
DR Gramene; AT1G51600.1; AT1G51600.1; AT1G51600.
DR Gramene; AT1G51600.2; AT1G51600.2; AT1G51600.
DR KEGG; ath:AT1G51600; -.
DR Araport; AT1G51600; -.
DR TAIR; locus:2017582; AT1G51600.
DR eggNOG; KOG1601; Eukaryota.
DR HOGENOM; CLU_057264_0_1_1; -.
DR InParanoid; Q8H1G0; -.
DR OMA; EKCTPMM; -.
DR OrthoDB; 1089061at2759; -.
DR PhylomeDB; Q8H1G0; -.
DR PRO; PR:Q8H1G0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8H1G0; baseline and differential.
DR Genevisible; Q8H1G0; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR010402; CCT_domain.
DR InterPro; IPR045280; TIFY-like.
DR InterPro; IPR010399; Tify_dom.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR46125; PTHR46125; 1.
DR Pfam; PF06203; CCT; 1.
DR Pfam; PF00320; GATA; 1.
DR Pfam; PF06200; tify; 1.
DR SMART; SM00979; TIFY; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR PROSITE; PS51017; CCT; 1.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
DR PROSITE; PS51320; TIFY; 1.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..302
FT /note="GATA transcription factor 28"
FT /id="PRO_0000083454"
FT DOMAIN 77..112
FT /note="Tify"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00650"
FT DOMAIN 147..189
FT /note="CCT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00357"
FT ZN_FING 217..273
FT /note="GATA-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT REGION 47..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 164
FT /note="D -> G (in Ref. 4; AAK76580)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 302 AA; 33130 MW; 326F63583D2409D5 CRC64;
MDDLHGSNAR MHIREAQDPM HVQFEHHALH HIHNGSGMVD DQADDGNAGG MSEGVETDIP
SHPGNVTDNR GEVVDRGSEQ GDQLTLSFQG QVYVFDSVLP EKVQAVLLLL GGRELPQAAP
PGLGSPHQNN RVSSLPGTPQ RFSIPQRLAS LVRFREKRKG RNFDKKIRYT VRKEVALRMQ
RNKGQFTSAK SNNDEAASAG SSWGSNQTWA IESSEAQHQE ISCRHCGIGE KSTPMMRRGP
AGPRTLCNAC GLMWANKGAF RDLSKASPQT AQNLPLNKNE DANLETDHQI MITVANDISN
SQ
