ID   GATA2_ARATH             Reviewed;         264 AA.
AC   O49741;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=GATA transcription factor 2;
DE            Short=AtGATA-2;
GN   Name=GATA2; OrderedLocusNames=At2g45050; ORFNames=T14P1.14;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Columbia;
RX   PubMed=12139008; DOI=10.1023/a:1016062325584;
RA   Teakle G.R., Manfield I.W., Graham J.F., Gilmartin P.M.;
RT   "Arabidopsis thaliana GATA factors: organisation, expression and DNA-
RT   binding characteristics.";
RL   Plant Mol. Biol. 50:43-57(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [5]
RP   GENE FAMILY ORGANIZATION.
RX   PubMed=15084732; DOI=10.1104/pp.103.037788;
RA   Reyes J.C., Muro-Pastor M.I., Florencio F.J.;
RT   "The GATA family of transcription factors in Arabidopsis and rice.";
RL   Plant Physiol. 134:1718-1732(2004).
CC   -!- FUNCTION: Transcriptional activator that specifically binds 5'-GATA-3'
CC       or 5'-GAT-3' motifs within gene promoters. May be involved in the
CC       regulation of some light-responsive genes.
CC       {ECO:0000269|PubMed:12139008}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Mostly expressed in roots. Also expressed in
CC       flowers and leaves, and to a lower extent in stems.
CC       {ECO:0000269|PubMed:12139008}.
CC   -!- SIMILARITY: Belongs to the type IV zinc-finger family. Class A
CC       subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Y13649; CAA74000.1; -; mRNA.
DR   EMBL; CP002685; AEC10500.1; -; Genomic_DNA.
DR   EMBL; BT000921; AAN41321.1; -; mRNA.
DR   PIR; T52104; T52104.
DR   RefSeq; NP_182031.1; NM_130069.3.
DR   AlphaFoldDB; O49741; -.
DR   SMR; O49741; -.
DR   STRING; 3702.AT2G45050.1; -.
DR   PaxDb; O49741; -.
DR   PRIDE; O49741; -.
DR   EnsemblPlants; AT2G45050.1; AT2G45050.1; AT2G45050.
DR   GeneID; 819112; -.
DR   Gramene; AT2G45050.1; AT2G45050.1; AT2G45050.
DR   KEGG; ath:AT2G45050; -.
DR   Araport; AT2G45050; -.
DR   TAIR; locus:2055589; AT2G45050.
DR   eggNOG; KOG1601; Eukaryota.
DR   HOGENOM; CLU_045755_1_1_1; -.
DR   InParanoid; O49741; -.
DR   OMA; FAGTWSP; -.
DR   OrthoDB; 1477093at2759; -.
DR   PhylomeDB; O49741; -.
DR   PRO; PR:O49741; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; O49741; baseline and differential.
DR   Genevisible; O49741; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:TAIR.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0009416; P:response to light stimulus; IEP:TAIR.
DR   CDD; cd00202; ZnF_GATA; 1.
DR   Gene3D; 3.30.50.10; -; 1.
DR   InterPro; IPR016679; TF_GATA_pln.
DR   InterPro; IPR000679; Znf_GATA.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   Pfam; PF00320; GATA; 1.
DR   PIRSF; PIRSF016992; TF_GATA_plant; 1.
DR   SMART; SM00401; ZnF_GATA; 1.
DR   PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR   PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Metal-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..264
FT                   /note="GATA transcription factor 2"
FT                   /id="PRO_0000083431"
FT   ZN_FING         175..229
FT                   /note="GATA-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT   REGION          29..57
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          96..192
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           114..121
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        29..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..176
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   264 AA;  28864 MW;  7ADB367D15B5A776 CRC64;
     MDVYGLSSPD LLRIDDLLDF SNEDIFSASS SGGSTAATSS SSFPPPQNPS FHHHHLPSSA
     DHHSFLHDIC VPSDDAAHLE WLSQFVDDSF ADFPANPLGG TMTSVKTETS FPGKPRSKRS
     RAPAPFAGTW SPMPLESEHQ QLHSAAKFKP KKEQSGGGGG GGGRHQSSSS ETTEGGGMRR
     CTHCASEKTP QWRTGPLGPK TLCNACGVRF KSGRLVPEYR PASSPTFVLT QHSNSHRKVM
     ELRRQKEVMR QPQQVQLHHH HHPF